TGM4 Antibody

Datasheet

Code	CSB-PA038312
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA038312(TGM4 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA038312(TGM4 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Hela, lncap, skov3, 293T and TM4 cell, Primary antibody: CSB-PA038312(TGM4 Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

P49221

Target Names

TGM4

Alternative Names

Dorsal prostate transglutaminase antibody; Dorsal protein 1 antibody; Dp1 antibody; Fibrinoligase antibody; hTGP antibody; Prostate specific transglutaminase antibody; Prostate transglutaminase antibody; Prostate-specific transglutaminase antibody; Protein glutamine gamma glutamyltransferase 4 antibody; Protein-glutamine gamma-glutamyltransferase 4 antibody; TG(P) antibody; TGase P antibody; TGase-4 antibody; TGase4 antibody; Tgm4 antibody; TGM4_HUMAN antibody; TGP antibody; Transglutaminase 4 (prostate) antibody; Transglutaminase 4 antibody; Transglutaminase P antibody; Transglutaminase, prostate antibody; Transglutaminase-4 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Fusion protein of Human TGM4

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Associated with the mammalian reproductive process. Catalyzes the cross-linking of proteins and the conjugation of polyamines to specific proteins in the seminal tract.

Gene References into Functions

TGM4 is a prostatic secretory molecule with critical role in male reproduction. PMID: 26084804
indicated that transglutaminase 4 may serve as a potential predictor of biochemical recurrence of prostate cancer PMID: 23974364
Evidence that the retinoic acid receptor gamma plays a major role in the regulation of the hTGP gene and that presence of the androgen receptor, but not its transcriptional transactivation activity, is critical for hTGP transcription. PMID: 22362749
CDKN2A, GATA3, CREBBP, ITGA2, NBL1 and TGM4 were down-regulated in the prostate carcinoma glands compared to the corresponding normal glands PMID: 21743959
The presence of TGase-4 has a biological impact on a prostate cancer cell's response to MDA-7. PMID: 21524313
TGase-4 expression is intrinsically linked to the activation of RON in prostate cancer cells and that this autoactivation of RON contributes to the increased cell motility in TGase-4 expressing cells. PMID: 20596668
The expression status of human transglutaminase 4 in benign prostate hyperplasia (BPH) and prostate cancer was analyzed. PMID: 20177144
transglutaminase 4 has a relatively wide profile of expression in human cancer cell lines PMID: 17552366
TGase-4 plays a pivotal role in the interaction between endothelial cells and prostate cancer cells, an action which is independent of the ROCK pathway. PMID: 18983858

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Protein Families

Transglutaminase superfamily, Transglutaminase family

Tissue Specificity

Prostate.

Database Links

HGNC: 11780

OMIM: 600585

KEGG: hsa:7047

STRING: 9606.ENSP00000296125

UniGene: Hs.438265

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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