TIPARP Antibody, FITC conjugated

Datasheet

Code	CSB-PA801800LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TIPARP Polyclonal antibody

Uniprot No.

Q7Z3E1

Target Names

TIPARP

Alternative Names

ADP-ribosyltransferase diphtheria toxin-like 14 antibody; ARTD14 antibody; AW558171 antibody; DDF1 antibody; DKFZp434J214 antibody; DKFZp686N0351 antibody; DKFZp686P1838 antibody; FLJ40466 antibody; PARP 1 antibody; PARP 7 antibody; PARP-7 antibody; PARPT_HUMAN antibody; pART14 antibody; Poly [ADP ribose] polymerase 7 antibody; Poly [ADP-ribose] polymerase 7 antibody; TCDD inducible poly(ADP ribose) polymerase antibody; TCDD-inducible poly [ADP-ribose] polymerase antibody; TIPARP antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human TCDD-inducible poly [ADP-ribose] polymerase protein (74-178AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins. Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR.

Gene References into Functions

TIPARP is a viral RNA-sensing pattern recognition receptors that mediates antiviral responses triggered by BAX- and BAK1-dependent mitochondrial damage PMID: 28213497
Moreover, time course and promoter activity assays suggest that TIPARP and TIPARP-AS1 work in concert to regulate AHR signaling. Collectively, these data show an added level of complexity in the AHR signaling cascade which involves lncRNAs, whose functions remain poorly understood. PMID: 29274782
Knockdown of TiPARP, but not AHRR, increased 2,3,7,8-tetrachlorodibenzo-p-dioxin - induced CYP1A1 mRNA and AHR protein levels. PMID: 24806346
Single nucleotide polymorphism in TIPARP is associated with ovarian cancer. PMID: 20852632
TIPARP (DKFZp434J214) gene is amplified in HNSCC. TIPARP, FLJ22693 and ZAP proteins with TPH, WW and PARP-like domains constitute the TIPARP family. PMID: 12851707

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Subcellular Location

Nucleus.

Database Links

HGNC: 23696

OMIM: 612480

KEGG: hsa:25976

STRING: 9606.ENSP00000295924

UniGene: Hs.744050

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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