TLR2 Antibody

Datasheet
Code CSB-PA080185
Size US$167
Uniprot No. O60603
Image
  • Immunohistochemical analysis of paraffin-embedded Mouse Spleen Tissue using TLR2 Polyclonal Antibody.

Protocols Immunohistochemistry (IHC) Protocol
ELISA Protocol
Immunogen Recombinant Protein
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications IHC,ELISA;IHC:1:200-500.ELISA:1/10000
Form Liquid
Conjugate Non-conjugated
Storage Buffer PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Isotype IgG
Alias Toll-like receptor 2
Immunogen Species Homo sapiens (Human)
Target Names TLR2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides
Subcellular Location Membrane, Single-pass type I membrane protein, Cytoplasmic vesicle, phagosome membrane, Single-pass type I membrane protein, Membrane raft
Protein Families Toll-like receptor family
Tissue Specificity Highly expressed in peripheral blood leukocytes, in particular in monocytes, in bone marrow, lymph node and in spleen. Also detected in lung and in fetal liver. Levels are low in other tissues.
Database Links

HGNC: 11848

OMIM: 246300

KEGG: hsa:7097

STRING: 9606.ENSP00000260010

UniGene: Hs.519033

Pathway PI3K-Akt signaling pathway
Toll-like receptor signaling pathway

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