TP73 Antibody, Biotin conjugated

Datasheet
Code CSB-PA024092OD01HU
Size US$299
Uniprot No. O15350
Immunogen Peptide sequence from Human Tumor protein p73 protein (537-555AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Tumor protein p73 (p53-like transcription factor) (p53-related protein), TP73, P73
Immunogen Species Human
Protocols ELISA Protocol
Research Area Cell Biology
Target Names TP73
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Subcellular Location Nucleus, Cytoplasm
Protein Families P53 family
Tissue Specificity Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue.
Database Links

HGNC: 12003

OMIM: 601990

KEGG: hsa:7161

STRING: 9606.ENSP00000367545

UniGene: Hs.192132

Pathway Hippo signaling pathway
p53 signaling pathway
Neurotrophin signaling pathway

Related Products

TP73 Antibodies

TP73 Antibodies for Human

TP73 Antibodies for Homo sapiens (Human)

TP73 Proteins

TP73 Proteins for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now!

We don't deal in spam.