TPSB2 Antibody

Datasheet

Code	CSB-PA024128LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA024128LA01HU at dilution of 1:100 Western Blot Positive WB detected in: Rat liver tissue, Rat kidney tissue, Mouse liver tissue, Mouse kidney tissue, Mouse stomach tissue All lanes: TPSB2 antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TPSB2 Polyclonal antibody

Uniprot No.

P20231

Target Names

TPSB2

Alternative Names

Mast cell tryptase beta II antibody; Mast cell tryptase beta III antibody; TPS2 antibody; TPSB2 antibody; TRYB2_HUMAN antibody; Tryptase beta 2 (gene/pseudogene) antibody; Tryptase beta-2 antibody; Tryptase II antibody; Tryptase-2 antibody; TryptaseB antibody; TryptaseC antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Tryptase beta-2 protein (31-275AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TPSB2 Antibody (Product code: CSB-PA024128LA01HU) is Non-conjugated. For TPSB2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA024128LB01HU	TPSB2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA024128LC01HU	TPSB2 Antibody, FITC conjugated
Biotin	CSB-PA024128LD01HU	TPSB2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.

Gene References into Functions

These observations indicate that betaII-tryptase activity is post-translationally regulated by an allosteric disulfide bond. PMID: 24142694
Results indicate a key role for heparin in the activation of human betaI- and beta2-tryptase. PMID: 15567416
The disease severity and plasma tryptase levels were not affected by the number of alpha or beta tryptase alleles in mastocytosis patients. PMID: 17449330
Strong linkage of TPSAB1 and TPSB2 and pairing of deficiency alleles with functional alleles in observed haplotypes protect human subjects from "knockout" genomes and indeed from inheritance of fewer than 2 active alleles. PMID: 19748655

Subcellular Location

Secreted. Note=Released from the secretory granules upon mast cell activation.

Protein Families

Peptidase S1 family, Tryptase subfamily

Database Links

HGNC: 14120

OMIM: 191081

KEGG: hsa:64499

UniGene: Hs.405479

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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