TSPAN7 Antibody

Datasheet

Code	CSB-PA025165LA01HU
Size	US$166
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Image	Immunofluorescent analysis of HepG2 cells using CSB-PA025165LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA025165LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA025165LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TSPAN7 Polyclonal antibody

Uniprot No.

P41732

Target Names

TSPAN7

Alternative Names

A15 antibody; CCG B7 antibody; CD231 antibody; CD231 antigen antibody; Cell surface glycoprotein A15 antibody; DXS1692E antibody; Membrane component chromosome X surface marker 1 antibody; Membrane component X chromosome surface marker 1 antibody; MRX58 antibody; MXS1 antibody; T cell acute lymphoblastic leukemia associated antigen 1 antibody; T-cell acute lymphoblastic leukemia-associated antigen 1 antibody; TALLA 1 antibody; TALLA antibody; TALLA-1 antibody; TALLA1 antibody; Tetraspanin 7 antibody; Tetraspanin-7 antibody; TM4SF2 antibody; TM4SF2b antibody; Transmembrane 4 superfamily 2b antibody; Transmembrane 4 superfamily member 2 antibody; Transmembrane protein A15 antibody; TSN7_HUMAN antibody; Tspan 7 antibody; Tspan-7 antibody; TSPAN7 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Tetraspanin-7 protein (113-223AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TSPAN7 Antibody (Product code: CSB-PA025165LA01HU) is Non-conjugated. For TSPAN7 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA025165LB01HU	TSPAN7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA025165LC01HU	TSPAN7 Antibody, FITC conjugated
Biotin	CSB-PA025165LD01HU	TSPAN7 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May be involved in cell proliferation and cell motility.

Gene References into Functions

These results disclosed a previously uncharacterized role of TSPAN7 in the regulation of the expression and functional activity of DRD2 by postendocytic trafficking. PMID: 28223337
The role of TSPAN7 in immune system response to HIV-1 is reviewed. TSPAN7 appears to be a positive regulator of actin nucleation and stabilization, through the ARP2/3 complex. By doing so, TSPAN7 limits HIV-1 endocytosis and maintains viral particles on actin-rich dendrites for an efficient transfer toward T lymphocytes. PMID: 28620031
Elevated TSPAN7 may be associated with better outcomes for multiple myeloma patients. PMID: 25637218
Loss of TSPAN7 is associated with metastasis in clear-cell renal cell carcinoma. PMID: 22213152
This study identified that TSPAN7 as a key molecule for the functional maturation of dendritic spines via PICK1 and ampa receptor trafficking. PMID: 22445342
TM4SF2 was identified as a putative antigenic target in Wegener's granulomatosis PMID: 20951001
Studies indicate that The thymus leukemia (TL) antigen and CD8alphaalpha are interacting surface molecules that are expressed at the frontline of the mucosal immune system. PMID: 20850477
The interaction of VP26 with tetraspanin-7 plays an essential role in normal HSV-1 replication. PMID: 20630051
associated with spermatozoa PMID: 19535787
The role of TMSF2 in mental retardation PMID: 14735593
coding mutations in TSPAN7 are not associated with our cohort of autism patients PMID: 19339915

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Involvement in disease

Mental retardation, X-linked 58 (MRX58)

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

Tetraspanin (TM4SF) family

Tissue Specificity

Not solely expressed in T-cells. Expressed in acute myelocytic leukemia cells of some patients.

Database Links

HGNC: 11854

OMIM: 300096

KEGG: hsa:7102

STRING: 9606.ENSP00000367743

UniGene: Hs.441664

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Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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