TUBA1B Antibody

Code CSB-PA04189A0Rb
Size US$166
Order now
Image
  • Western blot
    All lanes: TUBA1B antibody at 12 μg/ml
    Lane 1: Mouse brain tissue
    Lane 2: Mouse liver tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 51, 38 kDa
    Observed band size: 51, 34, 75 kDa

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA04189A0Rb at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA04189A0Rb at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA04189A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TUBA1B Polyclonal antibody
Uniprot No.
Target Names
TUBA1B
Alternative Names
ta 2b antibody; Alpha tubulin antibody; Alpha-tubulin ubiquitous antibody; beta Ib tubulin antibody; CDCBM5 antibody; CDCBM6 antibody; fd02b12 antibody; K ALPHA 1 antibody; M40 antibody; OK/SW-cl.56 antibody; TBA1B_HUMAN antibody; TUBA1B antibody; TUBB1 antibody; TUBB2 antibody; TUBB5 antibody; tubulin alpha 1b antibody; Tubulin alpha-1B chain antibody; Tubulin alpha-ubiquitous chain antibody; Tubulin beta 1b antibody; Tubulin beta 2A antibody; tubulin beta 2A class IIa antibody; Tubulin beta antibody; tubulin beta chain antibody; tubulin beta class I antibody; tubulin beta-1 chain antibody; tubulin beta-2A chain antibody; tubulin beta-5 chain antibody; Tubulin K-alpha-1 antibody; tubulin; alpha; ubiquitous antibody; tubulin; beta 2A class IIa antibody; tubulin; beta polypeptide 2 antibody; tubulin; beta polypeptide antibody; tubulin; beta; class IIA antibody; wu:fd02b12 antibody; zgc:55461 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Tubulin alpha-1B chain protein (29-310AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TUBA1B Antibody (Product code: CSB-PA04189A0Rb) is Non-conjugated. For TUBA1B Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA04189B0Rb TUBA1B Antibody, HRP conjugated ELISA
FITC CSB-PA04189C0Rb TUBA1B Antibody, FITC conjugated
Biotin CSB-PA04189D0Rb TUBA1B Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Gene References into Functions
  1. Data show that retinal endothelial cells (HREC) treated with low molecular weight fraction of commercial 5% human serum albumin (LMWF5A) exhibit a rapid increase in the amount and distribution of acetylated alpha-tubulin. PMID: 27613088
  2. The C-terminal tail from the tubulin beta I isotype, but not the beta III isotype, formed contacts in the putative binding site of a recently discovered antineoplastic peptide that disrupts microtubule formation in glioma cells. PMID: 28290671
  3. TUBA1B/ESR1 gene interaction might play pivotal roles in the occurrence and development of Postmenopausal Osteoporosis. PMID: 26676054
  4. Taken together our data provide valuable information regarding the interaction of CK1delta and a-tubulin and a novel approach for the development of pharmacological tools to inhibit proliferation of cancer cells. PMID: 26996302
  5. Results suggest that lithium chloride (LiCl) treatments activate alpha-tubulin N-acetyltransferase 1 (alphaTAT1) by the inhibition of glycogen synthase kinase 3 beta (GSK-3beta) and promote the alpha-tubulin acetylation, and then elongate the primary cilia. PMID: 24760594
  6. NAD-dependent regulation of alpha-tubulin acetylation is mediated by SIRT2. PMID: 24814981
  7. Data indicate that the derivatives exhibited much better potency to inhibit tubulin polymerization but a decreased activity to inhibit Hsp27 chaperone function. PMID: 23767669
  8. Increased TUBA1B expression is associated with poor overall survival in hepatocellular carcinoma. PMID: 23625295
  9. ARHGAP21 is a Rho-GAP involved in cell-cell junction remodeling that affects migration and EMT through alpha-tubulin interaction and acetylation PMID: 23235160
  10. TQ induced a concentration- and time-dependent degradation of alpha/beta tubulin in both cancer cell types. PMID: 21881916
  11. the ethyl acetate extract of Lactuca sativa induced HL-60 cell death, which correlated with the acetylation of alpha-tubulin. PMID: 20204303
  12. Confocal microscopic analyses showed co-localization of the TaSP protein with alpha-tubulin and reciprocal immuno-co-precipitation experiments demonstrated an association of TaSP with alpha-tubulin in vivo. PMID: 20162433
  13. This protein has been found differentially expressed in the anterior cingulate cortex from patients with schizophrenia PMID: 20381070
  14. increased levels in paclitaxel-resistant breast cancer cells PMID: 12054644
  15. Candidate gene K-ALPHA-1 expression in malignant and non-malignant prostate tissue samples after microdissection. PMID: 17628775
  16. accumulation of alpha-synuclein might contribute to the pathogenesis of PD and other Lewy body diseases by promoting alterations in parkin and tubulin solubility PMID: 18195004
  17. N-terminal sequencing and blastx analysis as well as blocking with K-alpha1 tubulin-specific Ab identified the epithelial Ag as K-alpha1 tubulin[K-alpha1 tubulin] PMID: 18354170
  18. These results imply that MeCP2 is involved in the regulation of neuronal alpha-tubulin and add molecular evidence that reversal of the effects of MeCP2 deficiency is achievable PMID: 19174478
  19. Increased expression of centrosomal TUBA1B in atypical ductal hyperplasia and carcinoma of the breast is reported. PMID: 19215229
  20. alpha-tubulin interacted with ARL7. PMID: 19409876
  21. This protein has been found differentially expressed in the Wernicke's Area from patients with schizophrenia. PMID: 19405953

Show More

Hide All

Subcellular Location
Cytoplasm, cytoskeleton.
Protein Families
Tubulin family
Database Links

HGNC: 18809

OMIM: 602530

KEGG: hsa:10376

STRING: 9606.ENSP00000336799

UniGene: Hs.524390

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*