TUBA1B Antibody

1. Data show that retinal endothelial cells (HREC) treated with low molecular weight fraction of commercial 5% human serum albumin (LMWF5A) exhibit a rapid increase in the amount and distribution of acetylated alpha-tubulin. PMID: 27613088
2. The C-terminal tail from the tubulin beta I isotype, but not the beta III isotype, formed contacts in the putative binding site of a recently discovered antineoplastic peptide that disrupts microtubule formation in glioma cells. PMID: 28290671
3. TUBA1B/ESR1 gene interaction might play pivotal roles in the occurrence and development of Postmenopausal Osteoporosis. PMID: 26676054
4. Taken together our data provide valuable information regarding the interaction of CK1delta and a-tubulin and a novel approach for the development of pharmacological tools to inhibit proliferation of cancer cells. PMID: 26996302
5. Results suggest that lithium chloride (LiCl) treatments activate alpha-tubulin N-acetyltransferase 1 (alphaTAT1) by the inhibition of glycogen synthase kinase 3 beta (GSK-3beta) and promote the alpha-tubulin acetylation, and then elongate the primary cilia. PMID: 24760594
6. NAD-dependent regulation of alpha-tubulin acetylation is mediated by SIRT2. PMID: 24814981
7. Data indicate that the derivatives exhibited much better potency to inhibit tubulin polymerization but a decreased activity to inhibit Hsp27 chaperone function. PMID: 23767669
8. Increased TUBA1B expression is associated with poor overall survival in hepatocellular carcinoma. PMID: 23625295
9. ARHGAP21 is a Rho-GAP involved in cell-cell junction remodeling that affects migration and EMT through alpha-tubulin interaction and acetylation PMID: 23235160
10. TQ induced a concentration- and time-dependent degradation of alpha/beta tubulin in both cancer cell types. PMID: 21881916
11. the ethyl acetate extract of Lactuca sativa induced HL-60 cell death, which correlated with the acetylation of alpha-tubulin. PMID: 20204303
12. Confocal microscopic analyses showed co-localization of the TaSP protein with alpha-tubulin and reciprocal immuno-co-precipitation experiments demonstrated an association of TaSP with alpha-tubulin in vivo. PMID: 20162433
13. This protein has been found differentially expressed in the anterior cingulate cortex from patients with schizophrenia PMID: 20381070
14. increased levels in paclitaxel-resistant breast cancer cells PMID: 12054644
15. Candidate gene K-ALPHA-1 expression in malignant and non-malignant prostate tissue samples after microdissection. PMID: 17628775
16. accumulation of alpha-synuclein might contribute to the pathogenesis of PD and other Lewy body diseases by promoting alterations in parkin and tubulin solubility PMID: 18195004
17. N-terminal sequencing and blastx analysis as well as blocking with K-alpha1 tubulin-specific Ab identified the epithelial Ag as K-alpha1 tubulin[K-alpha1 tubulin] PMID: 18354170
18. These results imply that MeCP2 is involved in the regulation of neuronal alpha-tubulin and add molecular evidence that reversal of the effects of MeCP2 deficiency is achievable PMID: 19174478
19. Increased expression of centrosomal TUBA1B in atypical ductal hyperplasia and carcinoma of the breast is reported. PMID: 19215229
20. alpha-tubulin interacted with ARL7. PMID: 19409876
21. This protein has been found differentially expressed in the Wernicke's Area from patients with schizophrenia. PMID: 19405953

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HGNC: 18809

OMIM: 602530

KEGG: hsa:10376

STRING: 9606.ENSP00000336799

UniGene: Hs.524390