TUBB6 Antibody

Code CSB-PA880105LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western blot
    All lanes: TUBB6 antibody at 4μg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: MDA-MB-231 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 50 kDa
    Observed band size: 50 kDa

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA880105LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA880105LA01HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) TUBB6 Polyclonal antibody
Uniprot No. Q9BUF5
Target Names TUBB6
Alternative Names tubulin beta-6 chain-like antibody; class V beta-tubulin antibody; HsT1601 antibody; TBB6_HUMAN antibody; TUBB-5 antibody; TUBB6 antibody; Tubulin beta 6 chain antibody; tubulin beta 6 class V antibody; tubulin beta class V antibody; tubulin beta MGC4083 antibody; Tubulin beta-6 antibody; Tubulin beta-6 chain antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Tubulin beta-6 chain protein (1-446AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).
Gene References into Functions
  1. Findings enlarge the spectrum of tubulinopathies and emphasize that mutations of TUBB6 should be considered in patients with congenital non-progressive facial palsy. PMID: 29016863
  2. TUBB6 is an inhibitor of pyroptosis. PMID: 24173717
  3. Data indicate that leucine-rich repeat kinase 2 (LRRK2) selectively interacts with three beta-tubulin isoforms: TUBB, TUBB4, and TUBB6. PMID: 24275654
  4. betaV-tubulin expression is a potentially promising prognostic marker of malignancy. PMID: 22903939
  5. in colorectal cancer patients, there was a link between poor survival, the expression of TUBB3/TUBB6, and androgen receptor only in females PMID: 22438565
  6. The TUBB6 expression was largely decreased in most tumors. PMID: 20191564

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Subcellular Location Cytoplasm, cytoskeleton
Protein Families Tubulin family
Tissue Specificity Ubiquitous. Maximal expression in breast and lung, where it represents around 10% of all beta-tubulins. Largely decreased expression in most cancerous tissues.
Database Links

HGNC: 20776

OMIM: 615103

KEGG: hsa:84617

STRING: 9606.ENSP00000318697

UniGene: Hs.193491

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