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TUBB6 Antibody

Datasheet
Citations (2)
Code CSB-PA880105LA01HU
Size US$166
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Image
  • Western Blotting(WB) - TUBB6 Antibody

    Western blot
    All lanes: TUBB6 antibody at 4μg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: MDA-MB-231 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 50 kDa
    Observed band size: 50 kDa

  • Immunohistochemistry(IHC) 1- TUBB6 Antibody

    Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA880105LA01HU at dilution of 1:100

  • Immunohistochemistry(IHC) 2- TUBB6 Antibody

    Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA880105LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TUBB6 Polyclonal antibody
Uniprot No.
Q9BUF5
Target Names
TUBB6
Alternative Names
tubulin beta-6 chain-like antibody; class V beta-tubulin antibody; HsT1601 antibody; TBB6_HUMAN antibody; TUBB-5 antibody; TUBB6 antibody; Tubulin beta 6 chain antibody; tubulin beta 6 class V antibody; tubulin beta class V antibody; tubulin beta MGC4083 antibody; Tubulin beta-6 antibody; Tubulin beta-6 chain antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Tubulin beta-6 chain protein (1-446AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TUBB6 Antibody (Product code: CSB-PA880105LA01HU) is Non-conjugated. For TUBB6 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA880105LB01HU TUBB6 Antibody, HRP conjugated ELISA
FITC CSB-PA880105LC01HU TUBB6 Antibody, FITC conjugated
Biotin CSB-PA880105LD01HU TUBB6 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Related Products

TUBB6 Proteins

Customer Reviews and Q&A

■ Customer Reviews
Average Rating:
5.0 - 1 reviews

Submit a Review here

Applications : Immunostainings

Sample type: cell

Review: TUBB6 and TGFBI protein expression levels among NMIUC (pTa/pT1) and MIUC (pT2-pT4) (left panel), also NIUC (pTa) and IUC (pT1-pT4) (middle panel). TUBB6 and TGFBI immunostainings in bladder urothelial carcinoma tissue microarrays.

By Anonymous

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Target Background

Function
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Gene References into Functions
  1. Findings enlarge the spectrum of tubulinopathies and emphasize that mutations of TUBB6 should be considered in patients with congenital non-progressive facial palsy. PMID: 29016863
  2. TUBB6 is an inhibitor of pyroptosis. PMID: 24173717
  3. Data indicate that leucine-rich repeat kinase 2 (LRRK2) selectively interacts with three beta-tubulin isoforms: TUBB, TUBB4, and TUBB6. PMID: 24275654
  4. betaV-tubulin expression is a potentially promising prognostic marker of malignancy. PMID: 22903939
  5. in colorectal cancer patients, there was a link between poor survival, the expression of TUBB3/TUBB6, and androgen receptor only in females PMID: 22438565
  6. The TUBB6 expression was largely decreased in most tumors. PMID: 20191564

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Subcellular Location
Cytoplasm, cytoskeleton.
Protein Families
Tubulin family
Tissue Specificity
Ubiquitous. Maximal expression in breast and lung, where it represents around 10% of all beta-tubulins. Largely decreased expression in most cancerous tissues.
Database Links

HGNC: 20776

OMIM: 615103

KEGG: hsa:84617

STRING: 9606.ENSP00000318697

UniGene: Hs.193491

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Related pathways
Gap junction
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