UAP1 Antibody, Biotin conjugated

Code CSB-PA618067LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) UAP1 Polyclonal antibody
Uniprot No.
Target Names
UAP1
Alternative Names
AGX 1 antibody; AGX antibody; AGX-1 antibody; AGX-2 antibody; AGX1 antibody; Antigen X antibody; AntigenX antibody; SPAG 2 antibody; SPAG2 antibody; Sperm associated antigen 2 antibody; Sperm-associated antigen 2 antibody; UAP 1 antibody; uap1 antibody; UAP1_HUMAN antibody; UDP N acetylhexosamine pyrophosphorylase antibody; UDP N acteylglucosamine pyrophosphorylase 1 antibody; UDP-N-acetylglucosamine pyrophosphorylase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human UDP-N-acetylhexosamine pyrophosphorylase protein (1-522AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
Gene References into Functions
  1. Results identified an enzyme, UAP1, which is highly overexpressed in prostate cancer and protects cancer cells from endoplasmic reticulum stress conferring a growth advantage. PMID: 25241896
Subcellular Location
Cytoplasm. Note=In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.
Protein Families
UDPGP type 1 family
Tissue Specificity
Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
Database Links

HGNC: 12457

OMIM: 602862

KEGG: hsa:6675

STRING: 9606.ENSP00000356903

UniGene: Hs.492859

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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