VIPR2 Antibody, FITC conjugated

Datasheet
Code CSB-PA025860LC01HU
Size US$299
Uniprot No. P41587
Protocols ELISA Protocol
Immunogen Recombinant Human Vasoactive intestinal polypeptide receptor 2 protein (24-126AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Helodermin-preferring VIP receptor) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (PACAP-R3) (VPAC2), VIPR2, VIP2R
Immunogen Species Homo sapiens (Human)
Research Area Neuroscience
Target Names VIPR2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 2 family
Tissue Specificity Expressed in CD4+ T-cells, but not in CD8+ T-cells. Expressed in the T-cell lines Jurkat, Peer, MOLT-4, HSB, YT and SUP-T1, but not in the T-cell lines HARRIS and HuT 78.
Database Links

HGNC: 12695

OMIM: 601970

KEGG: hsa:7434

STRING: 9606.ENSP00000262178

UniGene: Hs.585052

Pathway cAMP signaling pathway

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