XPNPEP1 Antibody

Datasheet

Code	CSB-PA878859HA01HU
Size	US$166
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Image	Western blot All lanes: Xaa-Pro aminopeptidase 1 antibody at 8μg/ml Lane 1: Mouse small intestine tissue Lane 2: Mouse stomach tissue Lane 3: Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 70, 68, 75, 73 kDa Observed band size: 70 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA878859HA01HU at dilution of 1:100
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) XPNPEP1 Polyclonal antibody

Uniprot No.

Q9NQW7

Target Names

XPNPEP1

Alternative Names

Aminoacylproline aminopeptidase antibody; aminopeptidase P, cytosolic antibody; APP1 antibody; Cytosolic aminopeptidase P antibody; RP11 451M19.1 antibody; sAmp antibody; Soluble aminopeptidase P antibody; soluble antibody; X Pro aminopeptidase 1 antibody; X prolyl aminopeptidase (aminopeptidase P) 1 antibody; X prolyl aminopeptidase (Aminopeptidase P) 1 soluble antibody; X prolyl aminopeptidase 1 antibody; X prolyl aminopeptidase 1 soluble antibody; X-Pro aminopeptidase 1 antibody; X-prolyl aminopeptidase 1 antibody; Xaa Pro aminopeptidase 1 antibody; Xaa-Pro aminopeptidase 1 antibody; XPNPEP 1 antibody; XPNPEP antibody; xpnpep1 antibody; XPNPEPL antibody; XPNPEPL1 antibody; XPP1_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Xaa-Pro aminopeptidase 1 protein (2-623AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The XPNPEP1 Antibody (Product code: CSB-PA878859HA01HU) is Non-conjugated. For XPNPEP1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA878859HB01HU	XPNPEP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA878859HC01HU	XPNPEP1 Antibody, FITC conjugated
Biotin	CSB-PA878859HD01HU	XPNPEP1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.

Gene References into Functions

Alanine replacement of Arg535 destabilizes the AMPP dimer and guanidine hydrochloride restores the native monomer-dimer equilibrium. It is proposed that Arg535 plays an important role in AMMP catalysis and in stabilization of the catalytically active dimeric state PMID: 29351301
These data suggest that progesterone-induced increases in AP-P may contribute to the development of oral contraceptive pill-induced hypertension in susceptible Women. PMID: 19126663

Subcellular Location

Cytoplasm.

Protein Families

Peptidase M24B family

Tissue Specificity

Expressed in all tissues tested, including pancreas, heart, muscle, kidney, liver, lung and brain. Highest levels in pancreas.

Database Links

HGNC: 12822

OMIM: 602443

KEGG: hsa:7511

STRING: 9606.ENSP00000421566

UniGene: Hs.390623

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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