Recombinant Danio rerio DNA damage-binding protein 2(ddb2)

Product Type Recombinant Protein
Uniprot No. Q2YDS1
Abbreviation ddb2
Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names ddb2
Protein Names Recommended name: DNA damage-binding protein 2 Alternative name(s): Damage-specific DNA-binding protein 2
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Required for DNA repair. Binds to ddb1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. Also appears to function as the substrate recognition module for a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex which may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair (By similarity).
Subcellular Location Nucleus
Protein Families WD repeat DDB2/WDR76 family
Database Links

UniGene: Dr.94422

Pathway p53 signaling pathway
DNA repair pathway
Ubiquitin mediated proteolysis

Product Details for Different Expression Systems

Product Name Recombinant Danio rerio DNA damage-binding protein 2(ddb2),Yeast
Code CSB-YP652125DIL
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MARGRAQTDS AASKQTKTVN SKKRPNEETP QPSTKKLKAK QQHKSKQKEE TYIQASVKWT GGQKKVGQTS ILHYIYKSSL GQSIHAQLRQ CLQEPFIRSL KSYKLHRTAS PFDRRVTSLE WHPTHPTTVA VGSKGGDIIL WDYDVLNKTS FIQGMGPGDA ITGMKFNQFN TNQLFVSSIW GATTLRDFSG SVIQVFAKTD SWDYWYCCVD VSVSRQMLAT GDSTGRLLLL GLDGHEIFKE KLHKAKVTHA EFNPRCDWLM ATSSVDATVK LWDLRNIKDK NSYIAEMPHE KPVNAAYFNP TDSTKLLTTD QRNEIRVYSS YDWSKPDQII IHPHRQFQHL TPIKATWHPM YDLIVAGRYP DDQLLLNDKR TIDIYDANSG GLVHQLRDPN AAGIISLNKF SPTGDVLASG MGFNILIWNR EDTLSSVNRK QTIVTGEDVG GRAGGSRSQR SSQQRPSRDR RAAADEAKLK KKLSATETKS KTKSKTESKT SKSKKK
Expression Region 1-496
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Danio rerio DNA damage-binding protein 2(ddb2),E.coli
Code CSB-EP652125DIL
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MARGRAQTDS AASKQTKTVN SKKRPNEETP QPSTKKLKAK QQHKSKQKEE TYIQASVKWT GGQKKVGQTS ILHYIYKSSL GQSIHAQLRQ CLQEPFIRSL KSYKLHRTAS PFDRRVTSLE WHPTHPTTVA VGSKGGDIIL WDYDVLNKTS FIQGMGPGDA ITGMKFNQFN TNQLFVSSIW GATTLRDFSG SVIQVFAKTD SWDYWYCCVD VSVSRQMLAT GDSTGRLLLL GLDGHEIFKE KLHKAKVTHA EFNPRCDWLM ATSSVDATVK LWDLRNIKDK NSYIAEMPHE KPVNAAYFNP TDSTKLLTTD QRNEIRVYSS YDWSKPDQII IHPHRQFQHL TPIKATWHPM YDLIVAGRYP DDQLLLNDKR TIDIYDANSG GLVHQLRDPN AAGIISLNKF SPTGDVLASG MGFNILIWNR EDTLSSVNRK QTIVTGEDVG GRAGGSRSQR SSQQRPSRDR RAAADEAKLK KKLSATETKS KTKSKTESKT SKSKKK
Expression Region 1-496
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Danio rerio DNA damage-binding protein 2(ddb2),Baculovirus
Code CSB-BP652125DIL
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MARGRAQTDS AASKQTKTVN SKKRPNEETP QPSTKKLKAK QQHKSKQKEE TYIQASVKWT GGQKKVGQTS ILHYIYKSSL GQSIHAQLRQ CLQEPFIRSL KSYKLHRTAS PFDRRVTSLE WHPTHPTTVA VGSKGGDIIL WDYDVLNKTS FIQGMGPGDA ITGMKFNQFN TNQLFVSSIW GATTLRDFSG SVIQVFAKTD SWDYWYCCVD VSVSRQMLAT GDSTGRLLLL GLDGHEIFKE KLHKAKVTHA EFNPRCDWLM ATSSVDATVK LWDLRNIKDK NSYIAEMPHE KPVNAAYFNP TDSTKLLTTD QRNEIRVYSS YDWSKPDQII IHPHRQFQHL TPIKATWHPM YDLIVAGRYP DDQLLLNDKR TIDIYDANSG GLVHQLRDPN AAGIISLNKF SPTGDVLASG MGFNILIWNR EDTLSSVNRK QTIVTGEDVG GRAGGSRSQR SSQQRPSRDR RAAADEAKLK KKLSATETKS KTKSKTESKT SKSKKK
Expression Region 1-496
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Danio rerio DNA damage-binding protein 2(ddb2),Mammalian cell
Code CSB-MP652125DIL
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MARGRAQTDS AASKQTKTVN SKKRPNEETP QPSTKKLKAK QQHKSKQKEE TYIQASVKWT GGQKKVGQTS ILHYIYKSSL GQSIHAQLRQ CLQEPFIRSL KSYKLHRTAS PFDRRVTSLE WHPTHPTTVA VGSKGGDIIL WDYDVLNKTS FIQGMGPGDA ITGMKFNQFN TNQLFVSSIW GATTLRDFSG SVIQVFAKTD SWDYWYCCVD VSVSRQMLAT GDSTGRLLLL GLDGHEIFKE KLHKAKVTHA EFNPRCDWLM ATSSVDATVK LWDLRNIKDK NSYIAEMPHE KPVNAAYFNP TDSTKLLTTD QRNEIRVYSS YDWSKPDQII IHPHRQFQHL TPIKATWHPM YDLIVAGRYP DDQLLLNDKR TIDIYDANSG GLVHQLRDPN AAGIISLNKF SPTGDVLASG MGFNILIWNR EDTLSSVNRK QTIVTGEDVG GRAGGSRSQR SSQQRPSRDR RAAADEAKLK KKLSATETKS KTKSKTESKT SKSKKK
Expression Region 1-496
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat

Related Products

ddb2 Antibodies

ddb2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.