Recombinant Human Interferon kappa(IFNK),Mammalian cell

Code CSB-MP889172HU
Product Type Recombinant Protein
Size Pls inquiry other sizes
Uniprot No. Q9P0W0
Abbreviation IFNK
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Purity >85% (SDS-PAGE)
Sequence LDC NLLNVHLRRV TWQNLRHLSS MSNSFPVECL RENIAFELPQ EFLQYTQPMK RDIKKAFYEM SLQAFNIFSQ HTFKYWKERH LKQIQIGLDQ QAEYLNQCLE EDKNENEDMK EMKENEMKPS EARVPQLSSL ELRRYFHRID NFLKEKKYSD CAWEIVRVEI RRCLYYFYKF TALFRRK
Source Mammalian cell
Gene Names IFNK
Protein Names Recommended name: Interferon kappa Short name= IFN-kappa
Expression Region 28-207
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Product Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Protein Description Full Length of Mature Protein
Target Details This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster.
HGNC 21714
RGD 1309045
MGI 2683287
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Function May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin.
Subcellular Location Secreted
Protein Families Alpha/beta interferon family
Tissue Specificity Expressed in keratinocytes, monocytes and in resting dendritic cells.
Database Links

HGNC: 21714

OMIM: 615326

KEGG: hsa:56832

STRING: 9606.ENSP00000276943

UniGene: Hs.591083

Pathway Jak-STAT signaling pathway

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