Recombinant Human Vascular endothelial growth factor B(VEGFB)

Code CSB-YP025834HU
Product Type Recombinant Protein
Size US$2010
Uniprot No. P49765
Relevance Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias VEGF-related factor ;VRF
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence PVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
Research Area Cancer
Source Yeast
Gene Names VEGFB
Protein Names Recommended name: Vascular endothelial growth factor B Short name= VEGF-B Alternative name(s): VEGF-related factor Short name= VRF
Expression Region 22-207aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 21.4kDa
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Subcellular Location Secreted
Protein Families PDGF/VEGF growth factor family
Tissue Specificity Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
Database Links

HGNC: 12681

OMIM: 601398

KEGG: hsa:7423

STRING: 9606.ENSP00000311127

UniGene: Hs.732095

Pathway MAPK signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Ras signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Rap1 signaling pathway

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