An NDA sequence corresponding to the 450-552aa of mouse Muellerian-inhibiting factor (Amh) was expressed with an N-terminal 6xHis-tag in the yeast. The resulting protein is the Recombinant partial-length Mouse Mullerian-inhibiting factor (Amh), which has a predicted molecular weight of 13.3 kDa. And it was purified by SDS-PAGE and reached up to 90% in purity. This Amh protein is in-stock, allowing the purchase of no waiting period of product preparation. It may be used as an immunogen for antibody production and in the studies related to sexual differentiation and germ development.
Amh is a gonadal hormone belonging to the transforming growth factor-beta family. It is restrictedly expressed in Sertoli cells of the fetal and adult testis and granulosa cells of the postnatal ovary. And it plays a significant role in sexual differentiation and germ development. Lack of Amh during female fetal development leads to the development of the Muellerian duct system. And Amh serves as an inhibitor of follicular development and recruitment, which contributes to follicular arrest.
Elevated expression of Amh is correlated with the various reproductive and metabolic/endocrine alterations in polycystic ovary syndrome (PCOS).
||Greater than 90% as determined by SDS-PAGE.
||Amh; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance; MIS
||Mus musculus (Mouse)
|Target Protein Sequence
Note: The complete sequence including tag
sequence, target protein sequence and linker sequence could be provided upon request.
Liquid or Lyophilized powder
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
|| If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the
glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer,
6% Trehalose, pH 8.0.
||We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
||Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
||The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
||Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
||Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
|Datasheet & COA
|| Please contact us to get it.