Recombinant Xiphophorus maculatus Cellular tumor antigen p53(tp53)

Product Type Recombinant Protein
Uniprot No. Q92143
Abbreviation tp53
Species Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
Gene Names tp53
Protein Names Recommended name: Cellular tumor antigen p53 Alternative name(s): Tumor suppressor p53
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity).
Subcellular Location Cytoplasm, Nucleus
Protein Families P53 family
Database Links

KEGG: xma:102219062

STRING: 8083.ENSXMAP00000015753

Pathway MAPK signaling pathway
p53 signaling pathway
PI3K-Akt signaling pathway
Wnt signaling pathway
Apoptosis
Cell cycle
Mitophagy
Cellular senescence
Cell ageing and metabolism
Sphingolipid signaling pathway
Neurotrophin signaling pathway

Product Details for Different Expression Systems

Product Name Recombinant Xiphophorus maculatus Cellular tumor antigen p53(tp53),Yeast
Code CSB-YP835627XAS
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MEEADLTLPL SQDTFHDLWN NVFLSTENES LPPPEGLLSQ NMDFWEDPET MQETKNVPTA PTVPAISNYA GEHGFNLEFN DSGTAKSVTS TYSVKLGKLF CQLAKTTPIG VLVKEEPPQG AVIRATAVYK KTEHVGEVVK RCPHHQSEDL SDNKSHLIRV EGSQLAQYFE DPNTRRHSVT VPYERPQLGS EMTTILLSFM CNSSCMGGMN RRPILTILTL ETTEGEVLGR RCFEVRVCAC PGRDRKTEEG NLEKSGTKQT KKRKSAPAPD TSTAKKSKSA SSGEDEDKEI YTLSIRGRNR YLWFKSLNDG LELMDKTGPK IKQEIPAPSS GKRLLKGGSD SD
Expression Region 1-342
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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Product Name Recombinant Xiphophorus maculatus Cellular tumor antigen p53(tp53),E.coli
Code CSB-EP835627XAS
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MEEADLTLPL SQDTFHDLWN NVFLSTENES LPPPEGLLSQ NMDFWEDPET MQETKNVPTA PTVPAISNYA GEHGFNLEFN DSGTAKSVTS TYSVKLGKLF CQLAKTTPIG VLVKEEPPQG AVIRATAVYK KTEHVGEVVK RCPHHQSEDL SDNKSHLIRV EGSQLAQYFE DPNTRRHSVT VPYERPQLGS EMTTILLSFM CNSSCMGGMN RRPILTILTL ETTEGEVLGR RCFEVRVCAC PGRDRKTEEG NLEKSGTKQT KKRKSAPAPD TSTAKKSKSA SSGEDEDKEI YTLSIRGRNR YLWFKSLNDG LELMDKTGPK IKQEIPAPSS GKRLLKGGSD SD
Expression Region 1-342
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Xiphophorus maculatus Cellular tumor antigen p53(tp53),Baculovirus
Code CSB-BP835627XAS
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MEEADLTLPL SQDTFHDLWN NVFLSTENES LPPPEGLLSQ NMDFWEDPET MQETKNVPTA PTVPAISNYA GEHGFNLEFN DSGTAKSVTS TYSVKLGKLF CQLAKTTPIG VLVKEEPPQG AVIRATAVYK KTEHVGEVVK RCPHHQSEDL SDNKSHLIRV EGSQLAQYFE DPNTRRHSVT VPYERPQLGS EMTTILLSFM CNSSCMGGMN RRPILTILTL ETTEGEVLGR RCFEVRVCAC PGRDRKTEEG NLEKSGTKQT KKRKSAPAPD TSTAKKSKSA SSGEDEDKEI YTLSIRGRNR YLWFKSLNDG LELMDKTGPK IKQEIPAPSS GKRLLKGGSD SD
Expression Region 1-342
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Xiphophorus maculatus Cellular tumor antigen p53(tp53),Mammalian cell
Code CSB-MP835627XAS
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MEEADLTLPL SQDTFHDLWN NVFLSTENES LPPPEGLLSQ NMDFWEDPET MQETKNVPTA PTVPAISNYA GEHGFNLEFN DSGTAKSVTS TYSVKLGKLF CQLAKTTPIG VLVKEEPPQG AVIRATAVYK KTEHVGEVVK RCPHHQSEDL SDNKSHLIRV EGSQLAQYFE DPNTRRHSVT VPYERPQLGS EMTTILLSFM CNSSCMGGMN RRPILTILTL ETTEGEVLGR RCFEVRVCAC PGRDRKTEEG NLEKSGTKQT KKRKSAPAPD TSTAKKSKSA SSGEDEDKEI YTLSIRGRNR YLWFKSLNDG LELMDKTGPK IKQEIPAPSS GKRLLKGGSD SD
Expression Region 1-342
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat

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