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TP53 gene, also known as P53, is an important tumor suppressor gene, which encodes a protein with a molecular weight of 53 kDa. The protein encoded by this gene is a transcription factor that controls the initiation of the cell cycle and plays a decisive role from the beginning of cell division. If the cell is damaged and cannot be repaired, the P53 protein will participate in the initiation process, causing the cell to die in apoptosis.
The central role of TP53 in cells is to mediate cellular emergency response after DNA damage, avoid accumulation of damaged DNA, and maintain genetic stability. In addition, TP53 is also involved in cell differentiation, regulation of senescence and inhibition of angiogenesis. The completion of these functions depends on the interaction between TP53 and DNA. As a transcription factor, TP53 can regulate the expression of various downstream genes. At present, there are more than 160 genes involved in the regulation of TP53, indicating that TP53 may play a very important role in the regulation of gene networks.
In addition, mutations in TP53, the most common genetic alteration in tumors, have been found in more than 50% of human tumors. When the TP53 gene is mutated, a tumor suppressor gene is converted into a tumor gene. The mutant TP53 lost its regulatory effects on cell growth, apoptosis and DNA repair due to its spatial conformational changes. Moreover, loss of TP53 function, which can also lead to cell resistance to radiation and chemical drugs, is a harbinger of radiotherapy and chemotherapy failure.
TP53 Monoclonal Antibody (ELISA,WB,IHC) (CSB-MA0240771A0m)
The following TP53 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TP53 Antibodies for Rattus norvegicus (Rat)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA15509A0Rb | Tp53 Antibody |
Rat, Mouse | ELISA, WB |
| CSB-PA15509C0Rb | Tp53 Antibody, FITC conjugated |
Rat |
TP53 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA024077GA01HU | TP53 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA07889C0Rb | TP53 Antibody, FITC conjugated |
Human | |
| CSB-PA07889D0Rb | TP53 Antibody, Biotin conjugated |
Human | ELISA |
| CSB-MA0240771A0m | TP53 Monoclonal Antibody |
Human | ELISA,WB,IHC |
| CSB-PA572207 | Phospho-TP53 (Ser6) Antibody |
Human,Mouse | ELISA,WB,IHC |
| CSB-PA157242 | Phospho-TP53 (Ser15) Antibody |
Human | ELISA,WB,IHC,IF |
| CSB-PA109326 | Phospho-TP53 (Thr18) Antibody |
Human | ELISA,WB |
| CSB-PA029276 | Phospho-TP53 (Ser33) Antibody |
Human | ELISA,WB,IF |
| CSB-PA445853 | Phospho-TP53 (Ser37) Antibody |
Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA945066 | Phospho-TP53 (Ser46) Antibody |
Human | ELISA,WB,IF |
| CSB-PA826876 | Phospho-TP53 (Ser315) Antibody |
Human | ELISA,WB,IHC,IF |
| CSB-PA277007 | TP53 (Ab-6) Antibody |
Human,Mouse | ELISA,WB |
| CSB-PA599282 | TP53 (Ab-9) Antibody |
Human | ELISA,WB |
| CSB-PA063047 | TP53 (Ab-15) Antibody |
Human | ELISA,WB,IHC,IF |
| CSB-PA992550 | TP53 (Ab-18) Antibody |
Human | ELISA,WB |
| CSB-PA593512 | TP53 (Ab-33) Antibody |
Human | ELISA,WB |
| CSB-PA923986 | TP53 (Ab-37) Antibody |
Human | ELISA,WB |
| CSB-PA445446 | TP53 (Ab-46) Antibody |
Human | ELISA,WB |
| CSB-PA964395 | TP53 (Ab-315) Antibody |
Human | ELISA,WB |
| CSB-PA226168 | Phospho-TP53 (Ser20) Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA449705 | Phospho-TP53 (Ser366) Antibody |
Human,Rat | ELISA,WB |
| CSB-PA052612 | Phospho-TP53 (Ser392) Antibody |
Human | ELISA,WB |
| CSB-PA870744 | TP53 (Ab-378) Antibody |
Human,Mouse | ELISA,WB |
| CSB-PA000096 | Di-Methyl-TP53 (K370) Antibody |
Human | WB, ELISA |
| CSB-PA000123 | Acetyl-TP53 (K370) Antibody |
Human | WB, ELISA |
| CSB-PA000124 | Acetyl-TP53 (K372) Antibody |
Human | WB, ELISA |
| CSB-PA000135 | Acetyl-TP53 (K373) Antibody |
Human | WB, ELISA |
| CSB-PA000136 | Acetyl-TP53 (K382) Antibody |
Human | WB, ELISA |
| CSB-PA000140 | Acetyl-TP53 (K320) Antibody |
Human | WB, ELISA |
| CSB-PA000595 | Phospho-TP53 (S15) Antibody |
Human,Rat | WB, IHC, IP, IF, ELISA |
| CSB-PA000596 | Phospho-TP53 (S20) Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA000597 | Phospho-TP53 (S315) Antibody |
Human | WB, IHC, IP, ELISA |
| CSB-PA000598 | Phospho-TP53 (S33) Antibody |
Human | WB, ELISA |
| CSB-PA000599 | Phospho-TP53 (S46) Antibody |
Human,Monkey | WB, ELISA |
| CSB-PA000600 | Phospho-TP53 (S6) Antibody |
Human,Monkey | WB, IHC, IP, ELISA |
| CSB-PA000602 | Phospho-TP53 (S9) Antibody |
Human,Monkey | WB, IHC, ELISA |
| CSB-PA000603 | Phospho-TP53 (T18) Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA000632 | Phospho-TP53 (S37) Antibody |
Human | WB, IHC, ELISA |
| CSB-PA003666 | TP53 Antibody |
Human,Monkey | WB, ELISA |
| CSB-PA003667 | TP53 Antibody |
Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA003668 | TP53 Antibody |
Human,Monkey | WB, IHC, IF, ELISA |
| CSB-PA003670 | TP53 Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA003672 | TP53 Antibody |
Human,Monkey | WB, IHC, IF, ELISA |
| CSB-PA003675 | TP53 Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA003676 | TP53 Antibody |
Human | WB, ELISA |
| CSB-PA003677 | TP53 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA003678 | TP53 Antibody |
Human,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-PA003680 | TP53 Antibody |
Human | WB, IHC, IF, ELISA |
| CSB-PA005967 | TP53 Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA050291 | Acetyl-TP53 (K317) Antibody |
Human | WB, IHC, IF, ELISA |
| CSB-PA050292 | Acetyl-TP53 (K381) Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA050293 | Acetyl-TP53 (K386) Antibody |
Human | IHC, IF, ELISA |
| CSB-PA050295 | Phospho-TP53 (S378) Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA050296 | Phospho-TP53 (S366) Antibody |
Human | WB, IHC, ELISA |
| CSB-PA050297 | Phospho-TP53 (S392) Antibody |
Human,Monkey | WB, IHC, IF, ELISA |
| CSB-PA050298 | Phospho-TP53 (T81) Antibody |
Human | IHC, ELISA |
| CSB-PA050299 | Phospho-TP53 (T387) Antibody |
Human | IHC, ELISA |
| CSB-PA050300 | Phospho-TP53 (S376) Antibody |
Human,Mouse,Rat | IHC, ELISA |
| CSB-PA050301 | TP53 Antibody |
Human | WB, IHC, ELISA |
| CSB-PA050302 | TP53 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA050303 | TP53 Antibody |
Human | WB, ELISA |
| CSB-PA050304 | TP53 Antibody |
Human | IHC, ELISA |
| CSB-PA050305 | TP53 Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-PA050306 | TP53 Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-PA080174 | TP53 Antibody |
Mouse,Rat | WB, IHC |
| CSB-MA080273 | Mono-Methyl-TP53(Lys370) Monoclonal Antibody |
Human,Mouse,Rat | ELISA,IHC |
| CSB-PA150453 | TP53 Antibody |
Human | ELISA,WB |
| CSB-PA07889A0Rb | TP53 Antibody |
Human, Mouse, Rat | ELISA, WB, IHC, ChIP |
| CSB-PA847762 | Phospho-TP53 (Ser366) Antibody |
Human | WB,ELISA |
| CSB-MA531279 | Acetyl-TP53(K382) Monoclonal Antibody |
Human,Mouse,Rat | ELISA,IHC |
| CSB-MA746672 | Acetyl-TP53(K382) Monoclonal Antibody |
Human,Mouse,Rat | ELISA,IHC |
| CSB-MA374487 | Acetyl-TP53(K382) Monoclonal Antibody |
Human,Mouse,Rat | ELISA,IHC |
| CSB-RA024077A55phHU | Phospho-TP53 (T55) Antibody |
Human | ELISA, WB, IF |
| CSB-RA024077A392phHU | Phospho-TP53 (S392) Antibody |
Human | ELISA, WB |
| CSB-RA024077A33phHU | Phospho-TP53 (S33) Antibody |
Human | ELISA, IHC, IF |
| CSB-RA024077A09phHU | Phospho-TP53 (S9) Antibody |
Human | ELISA, IF |
| CSB-RA236796A0HU | TP53 Antibody |
Human | ELISA, WB, IHC, IF |
| CSB-RA825742A0HU | TP53 Antibody |
Human | ELISA, WB, IHC, IF |
| CSB-RA214807A0HU | TP53 Antibody |
Human | ELISA, IHC |
| CSB-RA592348A0HU | TP53 Antibody |
Human | ELISA, IF |
TP53 Antibodies for Mus musculus (Mouse)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA024077LA01MO | Tp53 Antibody |
Mouse | ELISA |
| CSB-PA024077LB01MO | Tp53 Antibody, HRP conjugated |
Mouse | ELISA |
| CSB-PA024077LC01MO | Tp53 Antibody, FITC conjugated |
Mouse |
TP53 Antibodies for H
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-MA000208 | TP53 Monoclonal Antibody |
Human | ELISA,WB,IHC,IF |
TP53 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA024077XA01DIL | tp53 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
TP53 Proteins for Equus caballus (Horse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077HO CSB-EP024077HO CSB-BP024077HO CSB-MP024077HO CSB-EP024077HO-B |
Recombinant Horse Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077BO CSB-EP024077BO CSB-BP024077BO CSB-MP024077BO CSB-EP024077BO-B |
Recombinant Bovine Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Gallus gallus (Chicken)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077CH CSB-EP024077CH CSB-BP024077CH CSB-MP024077CH CSB-EP024077CH-B |
Recombinant Chicken Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Felis catus (Cat) (Felis silvestris catus)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077CA CSB-EP024077CA CSB-BP024077CA CSB-MP024077CA CSB-EP024077CA-B |
Recombinant Cat Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Ovis aries (Sheep)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077SH CSB-EP024077SH CSB-BP024077SH CSB-MP024077SH CSB-EP024077SH-B |
Recombinant Sheep Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Macaca mulatta (Rhesus macaque)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077MOW CSB-EP024077MOW CSB-BP024077MOW CSB-MP024077MOW CSB-EP024077MOW-B |
Recombinant Macaca mulatta (Rhesus macaque) Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077HU | Recombinant Human Cellular tumor antigen p53(TP53) |
Yeast |
| CSB-EP024077HU | Recombinant Human Cellular tumor antigen p53(TP53) |
E.coli |
| CSB-MP024077HU CSB-EP024077HU-B |
Recombinant Human Cellular tumor antigen p53(TP53) |
Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077MO CSB-BP024077MO CSB-MP024077MO CSB-EP024077MO-B |
Recombinant Mouse Cellular tumor antigen p53(Tp53) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP024077MO | Recombinant Mouse Cellular tumor antigen p53(Tp53) |
E.coli |
TP53 Proteins for Bos indicus (Zebu)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077BUL CSB-EP024077BUL CSB-BP024077BUL CSB-MP024077BUL CSB-EP024077BUL-B |
Recombinant Bos indicus Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Oryzias latipes (Japanese rice fish) (Japanese killifish)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077OFH CSB-EP024077OFH CSB-BP024077OFH CSB-MP024077OFH CSB-EP024077OFH-B |
Recombinant Oryzias latipes Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077DIL CSB-EP024077DIL CSB-BP024077DIL CSB-MP024077DIL CSB-EP024077DIL-B |
Recombinant Danio rerio Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077RA CSB-EP024077RA CSB-BP024077RA CSB-MP024077RA CSB-EP024077RA-B |
Recombinant Rat Cellular tumor antigen p53(Tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP155094r | Recombinant Rat Cellular tumor antigen p53(Tp53) |
E.coli |
TP53 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077DSU CSB-EP024077DSU CSB-BP024077DSU CSB-MP024077DSU CSB-EP024077DSU-B |
Recombinant Chlorocebus aethiops Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077OEI CSB-EP024077OEI CSB-BP024077OEI CSB-MP024077OEI CSB-EP024077OEI-B |
Recombinant Oncorhynchus mykiss Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077MOV CSB-EP024077MOV CSB-BP024077MOV CSB-MP024077MOV CSB-EP024077MOV-B |
Recombinant Macaca fascicularis Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Macaca fuscata fuscata (Japanese macaque)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077MMX CSB-EP024077MMX CSB-BP024077MMX CSB-MP024077MMX CSB-EP024077MMX-B |
Recombinant Macaca fuscata fuscata Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077XBE CSB-EP024077XBE CSB-BP024077XBE CSB-MP024077XBE CSB-EP024077XBE-B |
Recombinant Xenopus laevis Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077DXU CSB-EP024077DXU CSB-BP024077DXU CSB-MP024077DXU CSB-EP024077DXU-B |
Recombinant Cricetulus griseus Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Platichthys flesus (European flounder) (Pleuronectes flesus)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077EWX CSB-EP024077EWX CSB-BP024077EWX CSB-MP024077EWX CSB-EP024077EWX-B |
Recombinant Platichthys flesus Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Marmota monax (Woodchuck)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077MQG CSB-EP024077MQG CSB-BP024077MQG CSB-MP024077MQG CSB-EP024077MQG-B |
Recombinant Marmota monax Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Xiphophorus helleri (Green swordtail)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077XBJ CSB-EP024077XBJ CSB-BP024077XBJ CSB-MP024077XBJ CSB-EP024077XBJ-B |
Recombinant Xiphophorus helleri Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Ictalurus punctatus (Channel catfish) (Silurus punctatus)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024077ILX CSB-EP024077ILX CSB-BP024077ILX CSB-MP024077ILX CSB-EP024077ILX-B |
Recombinant Ictalurus punctatus Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP643685DO CSB-EP643685DO CSB-BP643685DO CSB-MP643685DO CSB-EP643685DO-B |
Recombinant Dog Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Equus asinus (Donkey) (Equus africanus asinus)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP645851DK CSB-EP645851DK CSB-BP645851DK CSB-MP645851DK CSB-EP645851DK-B |
Recombinant Donkey Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Spermophilus beecheyi (California ground squirrel) (Otospermophilus beecheyi)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP720691FJZ CSB-EP720691FJZ CSB-BP720691FJZ CSB-MP720691FJZ CSB-EP720691FJZ-B |
Recombinant Spermophilus beecheyi Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP835627XAS CSB-EP835627XAS CSB-BP835627XAS CSB-MP835627XAS CSB-EP835627XAS-B |
Recombinant Xiphophorus maculatus Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Delphinapterus leucas (Beluga whale)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP840473DJB CSB-EP840473DJB CSB-BP840473DJB CSB-MP840473DJB CSB-EP840473DJB-B |
Recombinant Delphinapterus leucas Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Oryctolagus cuniculus (Rabbit)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP856773RB CSB-EP856773RB CSB-BP856773RB CSB-MP856773RB CSB-EP856773RB-B |
Recombinant Rabbit Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Tupaia belangeri (Common tree shrew) (Tupaia glis belangeri)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP874674TRC CSB-EP874674TRC CSB-BP874674TRC CSB-MP874674TRC CSB-EP874674TRC-B |
Recombinant Tupaia belangeri Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Sus scrofa (Pig)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP880005PI CSB-EP880005PI CSB-BP880005PI CSB-MP880005PI CSB-EP880005PI-B |
Recombinant Pig Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Cavia porcellus (Guinea pig)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP892992GU CSB-EP892992GU CSB-BP892992GU CSB-MP892992GU CSB-EP892992GU-B |
Recombinant Guinea pig Cellular tumor antigen p53(TP53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Barbus barbus (Barbel) (Cyprinus barbus)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP894782BGAZ CSB-EP894782BGAZ CSB-BP894782BGAZ CSB-MP894782BGAZ CSB-EP894782BGAZ-B |
Recombinant Barbus barbus Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 Proteins for Tetraodon miurus (Congo puffer)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP895244TGAU CSB-EP895244TGAU CSB-BP895244TGAU CSB-MP895244TGAU CSB-EP895244TGAU-B |
Recombinant Tetraodon miurus Cellular tumor antigen p53(tp53) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TP53 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E08334h | Human p53/tumor protein,p53/TP53 ELISA Kit |
serum, cell culture supernates, urine, cerebrospinal fluid (CSF), tissue homogenates, cell lysates | 2.34 pg/mL |
TP53 ELISA Kit for Rattus norvegicus (Rat)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E08336r | Rat p53/tumor protein,p53/TP53 ELISA Kit |
serum, plasma, tissue homogenates | 3.12 pg/mL |
Cellular tumor antigen p53 is a protein in humans that is encoded by the TP53 gene. TP53 acts as a tumor suppressor in many tumor types. It induces growth arrest or apoptosis depending on the physiological circumstances and cell type. And it is also involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF, TP53 is involved in activating oxidative stress-induced necrosis, and the function is largely independent of transcription. Besides, it also induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.
