Code | CSB-RA799763A0HU |
Size | US$210 |
Order now | |
Image |
|
Have Questions? | Leave a Message or Start an on-line Chat |
Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
To produce the ALDH2 recombinant monoclonal antibody, four main steps are involved. The process begins with sequencing the ALDH2 monoclonal antibody gene. Next, the gene is cloned into a plasmid vector, which is then transfected into a host cell line. The ALDH2 recombinant monoclonal antibody is then purified from the cell culture supernatant by using affinity chromatography, after which it is tested and characterized. The ALDH2 monoclonal antibody is derived from ALDH2 antibody-producing hybridomas and is synthesized using a peptide derived from human ALDH2 as an immunogen. This type of recombinant monoclonal antibody is particularly useful in ELISA, WB, and IHC applications for the detection of ALDH2 proteins from human, mouse, and rat species.
ALDH2 is an enzyme that plays an essential role in alcohol metabolism in the liver. It converts toxic acetaldehyde, a byproduct of alcohol metabolism, into non-toxic acetate, which can be further metabolized and eliminated from the body. Additionally, ALDH2 has been shown to play a role in the metabolism of other aldehydes and in the detoxification of reactive oxygen species (ROS). Mutations in the ALDH2 gene have been associated with an increased risk of certain cancers and alcohol-related diseases.
There are currently no reviews for this product.