Code | CSB-RA217661A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
AR is a nuclear receptor transcription factor that regulates the cellular actions of androgens, the male sex steroids. It is found in a wide range of cells and tissues and has a role in the development and maintenance of the reproductive, musculoskeletal, cardiovascular, immunological, neurological, and hemopoietic systems, among others. Androgens can influence target gene transcription via the AR in a DNA binding-dependent manner, or they can activate fast, biological processes such as the phosphorylation of 2nd messenger signaling cascades in a non-DNA binding-dependent manner. Androgens and AR signaling are necessary for prostate development and homeostasis.
The recombinant AR antibody is a monoclonal antibody made in vitro using the AR antibody genes that are typically expressed from a plasmid in a stable mammalian cell line. The genes coding for the AR antibody will ultimately assemble into a fully functional antibody after translation. The synthesized antibody is the recombinant antibody against AR. It underwent purification using Affinity-chromatography. This recombinant AR antibody is suitable for use in the ELISA, WB, IHC to detect the AR protein from Human.There are currently no reviews for this product.