Code | CSB-RA147192A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
CEACAM1, also known as Cd66a, is a multi-functional receptor protein potentially expressed in epithelia, endothelia, and leukocytes. CEACAM1 has been implicated in various types of intercellular adhesion and intracellular signaling events important in cell survival, differentiation, and growth in both normal and cancer cells. CEACAM1 plays a dual role in different cancers either acting as a tumor suppressor or a tumor enhancer. Studies have shown that CEACAM1 expression in colon, hepatoma, and prostate cancers can inhibit tumor growth. CEACAM1 overexpression in thyroid and non-small cell cancer and melanomas is often associated with poor clinical outcomes and poor survival.
The recombinant CEACAM1 antibody was produced by cloning antibody genes into an expression vectors, which were subsequently introduced into mammalian cells to provide animal-free antibody production. This CEACAM1 antibody has been validated in ELISA, IHC. It has the features of improved affinity, stability, and consistency between different batches.There are currently no reviews for this product.