Code | CSB-RA289302A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:2000 |
The DDR2 recombinant monoclonal antibody synthesis is a meticulously orchestrated process. It all starts with in vitro cloning, where the genes encoding both DDR2 antibody's heavy and light chains are seamlessly incorporated into expression vectors. Following this, the expression vectors are introduced into host cells, enabling the recombinant antibody's expression within a cell culture environment. After expression, the antibody is carefully purified from the supernatant of transfected host cell lines, utilizing an affinity-chromatography purification method. This antibody can recognize both human and mouse DDR2 proteins in ELISA, WB, and FC applications.
DDR2 is a collagen receptor and receptor tyrosine kinase that plays a pivotal role in cell adhesion, migration, and tissue remodeling processes. Its functions are essential for normal development, tissue maintenance, and physiological responses to collagen-rich environments. Dysregulation of DDR2 signaling can have implications for various pathological conditions.
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