Code | CSB-RA787345A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
The production of the FBP1 recombinant monoclonal antibody is a multi-step process that involves several complex procedures. First, the FBP1 monoclonal antibody is extracted and its genetic code is identified through sequencing. Next, a vector containing the FBP1 monoclonal antibody gene is constructed and transfected into a host cell line for culturing. An immunogen used to generate the FBP1 monoclonal antibody is a human FBP1-derived peptide. The resulting FBP1 recombinant monoclonal antibody is then purified using affinity chromatography to ensure its high specificity and purity. Finally, the antibody is tested for its specificity in ELISA and IHC assays to confirm its ability to accurately detect FBP1. It only reacts with human FBP1 protein.
The FBP1 protein is an enzyme that plays a critical role in glucose metabolism, specifically in gluconeogenesis and the regulation of glycolysis. FBP1 catalyzes the hydrolysis of fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate, which is a key step in the gluconeogenic pathway. FBP1 catalyzes the hydrolysis of fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate, which is a key step in the gluconeogenic pathway. FBP1 has been shown to have tumor suppressor activity in various types of cancer, including liver, breast, and lung cancers. Loss of FBP1 expression has been associated with increased glucose uptake and glycolysis, which are hallmarks of cancer cells.
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