GPRC5D Recombinant Monoclonal Antibody

Code CSB-RA882153MA01HU
Size US$210
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  • The Binding Activity of Huamn GPRC5D with Anti-GPRC5D recombinant Antibody
    Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPRC5D(CSB-MP882153HU) at 5 μg/mL can bind Anti-GPRC5D recombinant antibody, the EC50 is 8.847-10.38 ng/mL.
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Product Details

Uniprot No.
Target Names
Alternative Names
GPRC5D; G-protein coupled receptor family C group 5 member D
Species Reactivity
Recombinant Human GPRC5D protein
Immunogen Species
Homo sapiens (Human)
Clone No.
Purification Method
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

The creation of the GPRC5D recombinant monoclonal antibody follows a meticulous and precise process to ensure its exceptional quality and specificity. It begins with the isolation of B cells from an immunized animal, where the recombinant human GPRC5D protein is used as the immunogen. Total RNA is extracted from these B cells and converted into cDNA through reverse transcription. The GPRC5D antibody genes are then amplified using specific primers designed for the antibody constant regions and inserted into an expression vector. Through transfection, the vector is introduced into host cells, enabling the production of the GPRC5D recombinant monoclonal antibody. Following a period of cell culture, the antibody is harvested from the supernatant and subjected to purification using affinity chromatography, resulting in a highly purified form suitable for diverse applications. CUSABIO performs ELISA to validate the antibody's specificity and functionality in detecting human GPRC5D protein.

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Target Background

Gene References into Functions
  1. GPRC5D in MM cells makes this gene and its encoded surface protein as promising markers for monitoring the tumor load and hopefully also as targets for antimyeloma antibodies. PMID: 23510526
  2. Overexpression of G protein-coupled receptor 5D in the bone marrow is associated with poor prognosis in patients with multiple myeloma. PMID: 22591013
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 3 family
Tissue Specificity
Widely expressed in the peripheral system. Expression pattern is high in pancreas, medium in kidney, small intestine, spleen and testis, low in lung, colon, leukocyte, prostate and thymus and not detectable in brain, heart, liver, placenta, skeletal muscl
Database Links

HGNC: 13310

OMIM: 607437

KEGG: hsa:55507

STRING: 9606.ENSP00000228887

UniGene: Hs.644599

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