GPRC5D Monoclonal Antibody

Code CSB-RA882153MA01HU
Size US$350
Image
  • The Binding Activity of Huamn GPRC5D with Anti-GPRC5D recombinant Antibody
    Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPRC5D(CSB-MP882153HU) at 5 μg/mL can bind Anti-GPRC5D recombinant antibody, the EC50 is 8.847-10.38 ng/mL.
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Product Details

Uniprot No. Q9NZD1
Target Names GPRC5D
Alternative Names GPRC5D; G-protein coupled receptor family C group 5 member D
Species Reactivity Human
Immunogen Recombinant Human GPRC5D protein
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Monoclonal
Isotype hIgG4(S228P)
Purification Method Affinity-chromatography
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. GPRC5D in MM cells makes this gene and its encoded surface protein as promising markers for monitoring the tumor load and hopefully also as targets for antimyeloma antibodies. PMID: 23510526
  2. Overexpression of G protein-coupled receptor 5D in the bone marrow is associated with poor prognosis in patients with multiple myeloma. PMID: 22591013
Subcellular Location Cell membrane; Multi-pass membrane protein.
Protein Families G-protein coupled receptor 3 family
Tissue Specificity Widely expressed in the peripheral system. Expression pattern is high in pancreas, medium in kidney, small intestine, spleen and testis, low in lung, colon, leukocyte, prostate and thymus and not detectable in brain, heart, liver, placenta, skeletal muscl
Database Links

HGNC: 13310

OMIM: 607437

KEGG: hsa:55507

STRING: 9606.ENSP00000228887

UniGene: Hs.644599

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