GPRC5D Research Reagents

G protein-coupled receptor, class C, group 5, member D (GPRC5D) is a G protein-coupled receptor C5 family subtype D, belonging to an orphan receptor. This protein is a 7-transmembrane protein with no known ligand or function in human and human cancers.

GPRC5D is widely expressed in malignant bone marrow plasma cells, hair follicles, and lungs, whereas in normal tissues, GPRC5D expression is very limited, with no or only low expression. Given the fact that GPRC5D is specifically highly expressed in multiple myeloma (MM), it has been considered as a new drug target in MM therapy. Presently, GPRC5D is attracting increased attention from many researchers and pharmaceutical companies. Currently, several drugs targeting GPRC5D or GPRC5D-based combinations are in clinical phase.

Validated Data

Antigen-antibody binding detected
by WB

CSB-MP882153HU is detected by Mouse anti-6*His monoclonal antibody.

The binding activity of antigen-antibody validated by functional ELISA

Immobilized Human GPRC5D at 5 μg/mL can bind Anti-GPRC5D recombinant antibody (CSB-RA882153MA01HU), the EC₅₀ is 8.847-10.38 ng/mL.

The following GPRC5D reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

GPRC5D Antibody

GPRC5D Protein

GPRC5D Antibodies

GPRC5D Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA030200	GPRC5D Antibody	Human,Mouse	WB, IF, ELISA
CSB-RA882153MA01HU	GPRC5D Monoclonal Antibody	Human	ELISA

GPRC5D Proteins

GPRC5D Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF878065MO	Recombinant Mouse G-protein coupled receptor family C group 5 member D(Gprc5d)	in vitro E.coli expression system
CSB-YP878065MO1 CSB-EP878065MO1 CSB-BP878065MO1 CSB-MP878065MO1 CSB-EP878065MO1-B	Recombinant Mouse G-protein coupled receptor family C group 5 member D(Gprc5d),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPRC5D Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF882153HU	Recombinant Human G-protein coupled receptor family C group 5 member D(GPRC5D)	in vitro E.coli expression system
CSB-YP882153HU1 CSB-BP882153HU1 CSB-MP882153HU1 CSB-EP882153HU1-B	Recombinant Human G-protein coupled receptor family C group 5 member D(GPRC5D),partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-MP882153HU	Recombinant Human G-protein coupled receptor family C group 5 member D(GPRC5D)-VLPs (Active)	Mammalian cell