GPRC5D (G Protein-Coupled Receptor Class C Group 5 Member D) is a transmembrane protein receptor that comprises an extracellular domain, a transmembrane domain, and a cytoplasmic domain. It is located on the cell membrane and can bind to specific signaling molecules, thereby initiating intracellular signal transduction. GPRC5D has been found to be highly expressed in B cells, especially in multiple myeloma (MM) cells. Research suggests that GPRC5D may play a significant role in the activation and proliferation of immune cells, particularly in the context of multiple myeloma, where it is considered a potential therapeutic target.
Validated Data
CSB-MP882153HU is detected by Mouse anti-6*His monoclonal antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPRC5D at 5 μg/mL can bind Anti-GPRC5D recombinant antibody (CSB-RA882153MA01HU), the EC50 is 8.847-10.38 ng/mL.
● GPRC5D Recombinant Monoclonal Antibody CSB-RA882153MA01HU
Validated Data
The Binding Activity of Huamn GPRC5D with Anti-GPRC5D recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPRC5D (CSB-MP882153HU) at 5 μg/mL can bind Anti-GPRC5D recombinant antibody, the EC50 is 8.847-10.38 ng/mL.
The following GPRC5D reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GPRC5D Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA030200 | GPRC5D Antibody |
Human,Mouse | WB, IF, ELISA |
CSB-RA882153MA01HU | GPRC5D Recombinant Monoclonal Antibody |
Human | ELISA |
GPRC5D Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF878065MO | Recombinant Mouse G-protein coupled receptor family C group 5 member D (Gprc5d) |
in vitro E.coli expression system |
CSB-YP878065MO1 CSB-EP878065MO1 CSB-BP878065MO1 CSB-MP878065MO1 CSB-EP878065MO1-B |
Recombinant Mouse G-protein coupled receptor family C group 5 member D (Gprc5d), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPRC5D Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF882153HU | Recombinant Human G-protein coupled receptor family C group 5 member D (GPRC5D) |
in vitro E.coli expression system |
CSB-YP882153HU1 CSB-BP882153HU1 CSB-MP882153HU1 CSB-EP882153HU1-B |
Recombinant Human G-protein coupled receptor family C group 5 member D (GPRC5D), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-MP882153HU | Recombinant Human G-protein coupled receptor family C group 5 member D (GPRC5D)-VLPs (Active) |
Mammalian cell |
CSB-EP882153HU1 | Recombinant Human G-protein coupled receptor family C group 5 member D (GPRC5D), partial |
E.coli |