Code | CSB-RA010385A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IF | 1:30-1:200 |
The recombinant monoclonal antibody against histone H2A type 1-B/E was prepared by transfecting the vector containing the DNA for the histone H2A type 1-B/Emonoclonal antibody into the cell lines for in vitro production. The product was purified using affinity chromatography to obtain the histone H2A type 1-B/E recombinant antibody. This antibody is a rabbit IgG and recognizes human histone H2A type 1-B/E. It has been tested and approved for use in ELISA, WB, and IF.
Histone proteins are required for the shift between active and inactive chromatin states, both structurally and functionally. Histones have evolved to play a variety of roles in gene regulation and epigenetic silencing, despite their high conservation due to restrictions to maintain the overall shape of the nucleosomal octameric core. DMA replication, transcription, repair, and recombination are influenced by histone variations, post-translational modifications, and interactions with chromatin remodeling complexes.
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