Code | CSB-RA146975A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
MIF is an inflammatory cytokine and a crucial innate immune system regulator. MIF overexpression has been associated with increased inflammation and immunopathology. Anti-MIF antibodies have been shown to effectively inhibit tumor development and tumor-associated angiogenesis, implying that MIF is implicated not only in inflammatory and immunological responses but also in tumor cell proliferation. MIF is overexpressed in a wide range of cancers. When binding to the CD74 receptor, MIF stimulates a number of cell signaling pathways, including the PI3K/AKT and MAPK signaling pathways, which increase tumor cell proliferation and survival.
The MIF antibody genes were cloned from B cells that were derived from immunized animals with A synthesized peptide derived from human MIF and then introduced into the plasma vectors, which were transfected into mammalian cell lines for up-scaling expression. The product was purified by A synthesized peptide derived from human MIF to obtain the recombinant antibody against MIF. This recombinant MIF antibody is reactive with the MIF protein from Human. It is recommended for use in the ELISA, WB.There are currently no reviews for this product.