Recombinant Human D(1A) dopamine receptor(DRD1)

Code CSB-CF007178HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P21728
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
Source in vitro E.coli expression system
Gene Names DRD1
Protein Names Recommended name: D(1A) dopamine receptorAlternative name(s): Dopamine D1 receptor
Expression Region 1-446
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Subcellular Location Cell membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 1 family
Tissue Specificity Detected in caudate, nucleus accumbens and in the olfactory tubercle.
Database Links

HGNC: 3020

OMIM: 126449

KEGG: hsa:1812

STRING: 9606.ENSP00000327652

UniGene: Hs.2624

Pathway Calcium signaling pathway
cAMP signaling pathway
Gap junction

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