Recombinant Human Interferon gamma receptor 1(IFNGR1)

Code CSB-CF011051HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P15260
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names IFNGR1
Protein Names Recommended name: Interferon gamma receptor 1 Short name= IFN-gamma receptor 1 Short name= IFN-gamma-R1 Alternative name(s): CDw119 CD_antigen= CD119
Expression Region 18-489
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG)
Involvement in disease Immunodeficiency 27A (IMD27A); Immunodeficiency 27B (IMD27B)
Subcellular Location Cell membrane, Single-pass type I membrane protein
Protein Families Type II cytokine receptor family
Database Links

HGNC: 5439

OMIM: 107470

KEGG: hsa:3459

STRING: 9606.ENSP00000356713

UniGene: Hs.520414

Pathway HIF-1 signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Osteoclast differentiation
Th1 and Th2 cell differentiation
Th17 cell differentiation

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