Recombinant Human Interferon gamma receptor 2(IFNGR2)

Code CSB-CF011052HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P38484
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names IFNGR2
Protein Names Recommended name: Interferon gamma receptor 2 Short name= IFN-gamma receptor 2 Short name= IFN-gamma-R2Alternative name(s): Interferon gamma receptor accessory factor 1 Short name= AF-1 Interferon gamma transducer 1
Expression Region 22-337
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG)
Involvement in disease Immunodeficiency 28 (IMD28)
Subcellular Location Cell membrane, Single-pass type I membrane protein, Cytoplasmic vesicle membrane, Single-pass type I membrane protein, Golgi apparatus membrane, Single-pass type I membrane protein, Endoplasmic reticulum membrane, Single-pass type I membrane protein, Cytoplasm
Protein Families Type II cytokine receptor family
Tissue Specificity Expressed in T-cells (at protein level).
Database Links

HGNC: 5440

OMIM: 147569

KEGG: hsa:3460

STRING: 9606.ENSP00000290219

UniGene: Hs.634632

Pathway HIF-1 signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Osteoclast differentiation
Th1 and Th2 cell differentiation
Th17 cell differentiation

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