Recombinant Human Tumor necrosis factor receptor superfamily member 13B protein(TNFRSF13B) (Active)

In Stock
Code CSB-AP002301HU
Product Type Tumor Necrosis Factor
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. O14836
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias Transmembrane activator and CAML interactor
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The biological activity is determined by its ability to block human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 ug/ml.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence MSGLGRSRRG GRSRVDQEER FPQGLWTGVA MRSCPEEQYW DPLLGTCMSC KTICNHQSQR TCAAFCRSLS CRKEQGKFYD HLLRDCISCA SICGQHPKQC AYFCENKLRS PVNLPPELRR QRSGEVENNS DNSGRYQGLE HRGSEASPAL PGLKLSADQV
Research Area Cancer
Source E.coli
Gene Names TNFRSF13B
Expression Region 1-160aa
Tag Info Tag-Free
Mol. Weight 18.0 kDa
Protein Description Partial
PubMed ID 9311921; 14702039; 15489334; 10956646; 10973284; 10880535; 15542592; 16007086; 21248752
Still Have Questions? Leave a Message or Start an on-line Chat
Function Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
Involvement in disease Immunodeficiency, common variable, 2 (CVID2); Immunoglobulin A deficiency 2 (IGAD2)
Subcellular Location Membrane, Single-pass type III membrane protein
Tissue Specificity Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.
Database Links

HGNC: 18153

OMIM: 240500

KEGG: hsa:23495

STRING: 9606.ENSP00000261652

UniGene: Hs.158341

Related Products

TNFRSF13B Antibodies

TNFRSF13B Antibodies for Homo sapiens (Human)

TNFRSF13B Antibodies for Human

TNFRSF13B Proteins

TNFRSF13B Proteins for Homo sapiens (Human)

TNFRSF13B ELISA Kit

TNFRSF13B ELISA Kit for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 20,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now to get your $50 coupon for protein expression service!

We don't deal in spam.