NPL Antibody

Datasheet

Code	CSB-PA874830LA01HU
Size	US$166
	Order now
Image	Western Blot Positive WB detected in: Mouse brain tissue All lanes: NPL antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 36, 34, 32, 27, 13 kDa Observed band size: 36 kDa Immunofluorescent analysis of Hela cells using CSB-PA874830LA01HU at dilution of 1: 100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The Latest Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) NPL Polyclonal antibody

Uniprot No.

Q9BXD5

Target Names

NPL

Alternative Names

0610033B02Rik antibody; C112 antibody; C1orf13 antibody; Dihydrodipicolinate synthase antibody; Dihydrodipicolinate synthetase homolog 1 antibody; MGC149582 antibody; MGC61869 antibody; N-acetylneuraminate lyase antibody; N-acetylneuraminate pyruvate-lyase antibody; N-acetylneuraminic acid aldolase antibody; NAL antibody; NALase antibody; NPL antibody; NPL_HUMAN antibody; NPL1 antibody; RP11-249O6.1 antibody; Sialate lyase antibody; Sialate-pyruvate lyase antibody; Sialic acid aldolase antibody; Sialic acid lyase antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human N-acetylneuraminate lyase protein (17-77AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The NPL Antibody (Product code: CSB-PA874830LA01HU) is Non-conjugated. For NPL Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA874830LB01HU	NPL Antibody, HRP conjugated	ELISA
FITC	CSB-PA874830LC01HU	NPL Antibody, FITC conjugated
Biotin	CSB-PA874830LD01HU	NPL Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Experiments show the true substrate is aceneuramate (linearized Neu5Ac).

Gene References into Functions

an NPL splice variant is mainly expressed in human liver, kidney and peripheral blood leukocytes PMID: 16147865
3D structure model of N-acetylneuraminate lyase from human (hNAL, EC 4.1.3.3) was created and refined PMID: 19057931

Subcellular Location

Cytoplasm.

Protein Families

DapA family, NanA subfamily

Tissue Specificity

Isoform 2 is expressed in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocyte.

Database Links

HGNC: 16781

OMIM: 611412

KEGG: hsa:80896

STRING: 9606.ENSP00000258317

UniGene: Hs.496969

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Streptococcus pneumoniae, a Primary Cause of Pneumonia Oct4 -- The Gatekeeper of Pluripotency of Embryonic Stem Cells Epitope Tags Overview Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address