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Recombinant Rat C-C motif chemokine protein (Ccl17) (Active)

Recombinant Rat C-C motif chemokine protein (Ccl17) (Active)

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Code	CSB-AP001571RA
Abbreviation	Recombinant Rat Ccl17 protein (Active)
MSDS	MSDS Datasheet
Size	$142
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Product Details
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Product Details

Purity

>97% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU/μg as determined by LAL method.

Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml.

Target Names

Ccl17

Uniprot No.

Q9ERE0

Research Area

Immunology

Species

Rattus norvegicus (Rat)

Source

E.coli

Expression Region

24-93aa

Complete Sequence

ARATNVGREC CLDYFKGAIP IRKLVTWFRT SVECPKDAIV FETVQGRLIC TDPKDKHVKK AIRHLKNQRL

Mol. Weight

8.1 kDa

Protein Length

Full Length of Mature Protein

Tag Info

Tag-Free

Form

Lyophilized powder

Buffer

Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

5-10 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Description

CCL17 (TARC) is a key CCR4 ligand that drives Th2 cell recruitment and plays a central role in allergic inflammation and skin-homing immune responses. This tag-free recombinant rat CCL17 encompasses the full-length mature sequence (residues 24–93) and demonstrates potent chemotactic activity on human T-lymphocytes at 1.0–10 ng/ml, providing a reliable basis for Transwell migration assays, CCR4 signaling studies, and in vivo models of atopic or inflammatory disease in rats. The endotoxin level of <1.0 EU/μg satisfies the stringent criteria needed to prevent LPS-driven artifacts in sensitive immune cell functional assays, including T-cell activation, Th2 polarization, and MAPK or NF-κB pathway dissection downstream of CCR4 engagement. Purity exceeding 97% by SDS-PAGE further supports use as a reference standard in CCL17 detection assays or as a coating antigen for antibody development and ELISA validation.