Recombinant Mouse Granulocyte-macrophage colony-stimulating factor protein(Csf2) (Active)

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Code CSB-AP003441MO
Product Type Colony Stimulating Factor
Size US$112Purchase it in Cusabio online store
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Uniprot No. P01587
Lead Time 5-10 business days
Image
Storage Buffer 0.2μm filtered PBS, pH 7.4 ,lyophilized
Alias GM-CSF, CSF
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine FDC-P1 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2.0x107 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence APTRSPITVT RPWKHVEAIK EALNLLDDMP VTLNEEVEVV SNEFSFKKLT CVQTRLKIFE QGLRGNFTKL KGALNMTASY YQTYCPPTPE TDCETQVTTY ADFIDSLKTF LTDIPFECKK PGQK
Research Area Immunology
Source E.coli
Gene Names Csf2
Expression Region 18-141aa
Tag Info Tag-Free
Mol. Weight 14.1 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3876930; 3876931; 3902470; 3874057; 6610831; 3898082; 3871523; 3318813; 2002066
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Function Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Subcellular Location Secreted
Protein Families GM-CSF family
Database Links

KEGG: mmu:12981

STRING: 10090.ENSMUSP00000019060

UniGene: Mm.4922

Pathway Jak-STAT signaling pathway
TNF signaling pathway
Fc epsilon RI signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway

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