zip Antibody

1. study highlights the activity and distribution controls of basal myosin contractility mediated by cell-matrix and cell-cell adhesions, respectively, during tissue morphogenesis PMID: 28406187
2. This study demonstrated that endogenous mechanical cues trigger biochemical pathways, generating the active morphogenetic movements shaping animal development through a mechanotransductive cascade of Myo-II medio-apical stabilization. PMID: 28112149
3. Analyzing the dynamics of junction shortening and elongation resulting from myosin II pulses, the authors find that long pulses yield less reversible deformations, typically a signature of dissipative mechanics. This is consistent with a simple viscoelastic description, which we use to model individual shortening and elongation events. PMID: 28988857
4. Migration of Drosophila border cells, a genetically tractable model for collective cell migration, requires nonmuscle myosin-II. PMID: 22326025
5. Nonmuscle myosin II is required for cell proliferation, cell sheet adhesion and wing hair morphology during wing morphogenesis PMID: 20599890
6. Our results provide evidence that Nonmuscle Myosin II is present presynaptically, is important for synaptic vesicle mobility and suggests a role for Nonmuscle Myosin II in shuttling vesicles at the Drosophila neuromuscular junction. PMID: 20233422
7. The c-Jun N-terminal kinase pathway is essential for this myosin II localization during wound healing. PMID: 20153725
8. zip/MyoII is responsible for generating the forces that drive cell-shape changes in each of the force-generating tissues that contribute to dorsal closure. PMID: 16360683
9. Myosin II, or Zipper (Zip), a motor protein, regulates the rate at which ommatidia rotate: in zip mutants, the rate of rotation is significantly slowed. PMID: 17826761
10. An MYH9 human disease model in flies. PMID: 17901043
11. myosin II regulates higher-order organization of cells in the plane of the epithelium PMID: 17981139
12. ectopically activating Hh signaling in fly epithelia reveals a direct relationship between the duration of exposure to this signaling pathway, the accumulation of activated Myosin II, and the degree of tissue invagination. PMID: 17981140
13. Miranda protein forms an apical crescent at interphase, but is ubiquitously localized at prophase in a Myosin-II-dependent manner. PMID: 18398000
14. S2 hinge region plays an important role in determining myosin kinetics and in regulating thick and thin filament lengths as well as sarcomere length. PMID: 19450484
15. results demonstrate that myosin II dynamics are regulated by tension in a positive feedback loop that leads to multicellular actomyosin cable formation and efficient tissue elongation. PMID: 19879198

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KEGG: dme:Dmel_CG15792

STRING: 7227.FBpp0072306

UniGene: Dm.2632