PPP2R2C Antibody

Code CSB-PA897535ZA01HU
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) PPP2R2C Polyclonal antibody
Uniprot No. Q9Y2T4
Target Names PPP2R2C
Alternative Names 2ABG_HUMAN antibody; B55 gamma antibody; Gamma isoform of regulatory subunit B55 protein phosphatase 2 antibody; IMYPNO 1 antibody; IMYPNO antibody; IMYPNO1 antibody; MGC33570 antibody; OTTHUMP00000115505 antibody; Phosphoprotein phosphatase 2A BR gamma regulatory chain antibody; PP2A subunit B B gamma isoform antibody; PP2A subunit B B55 gamma isoform antibody; PP2A subunit B isoform B55-gamma antibody; PP2A subunit B isoform gamma antibody; PP2A subunit B isoform PR55-gamma antibody; PP2A subunit B isoform R2-gamma antibody; PP2A subunit B PR55 gamma isoform antibody; PP2A subunit B R2 gamma isoform antibody; PPP2R2C antibody; PPP2R2C protein antibody; PR 52 antibody; PR 55G antibody; PR52 antibody; PR55G antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B gamma isoform antibody; Protein phosphatase 2 regulatory subunit B gamma antibody; Protein phosphatase 2 regulatory subunit B gamma isoform antibody; Protein phosphatase 2A1 B gamma subunit antibody; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform antibody; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform antibody
Raised in Rabbit
Species Reactivity Homo sapiens
Immunogen Recombinant Homo sapiens PPP2R2C protein
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (12-14 weeks)

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Target Background

(From Uniprot)
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Gene References into Functions
  1. B55gamma is induced by glucocorticoid receptor in human primary BM-MSCs during differentiation to osteoblast and is required for osteoblast morphogenesis. PMID: 28805158
  2. miR-572 promotes the proliferation and invasion of nasopharyngeal carcinoma by directly down-regulating PPP2R2C PMID: 28525724
  3. miR-1301 promoted prostate cancer proliferation by inhibiting PPP2R2C. PMID: 27261573
  4. These findings provide insights into mechanisms by which prostate cancers resist AR-pathway suppression and support inhibiting PPP2R2C complexes. PMID: 23493267
  5. PPP2R2C is a potential tumor suppressor gene in human brain cancers. PMID: 24126060
  6. evidence suggests that allelic variation in PPP2R2C may be associated with a variety of personality traits and ADHD per se. PMID: 22664926
  7. encoding a subunit of proteinphosphatase 2A with a unique expression pattern in brain and a role in synaptic plasticity PMID: 20601260
  8. specific PP2A complexes involved in human cell transformation PMID: 14998489
  9. novel mechanism of c-SRC regulation whereby in response to stress c-SRC activity is regulated, at least in part, through loss of the interaction with its inhibitor, PR55gamma PMID: 18069897

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Protein Families Phosphatase 2A regulatory subunit B family
Database Links

HGNC: 9306

OMIM: 605997

KEGG: hsa:5522

STRING: 9606.ENSP00000335083

UniGene: Hs.479069

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