Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PPP2R2C Polyclonal antibody

Uniprot No.

Q9Y2T4

Target Names

PPP2R2C

Alternative Names

2ABG_HUMAN antibody; B55 gamma antibody; Gamma isoform of regulatory subunit B55 protein phosphatase 2 antibody; IMYPNO 1 antibody; IMYPNO antibody; IMYPNO1 antibody; MGC33570 antibody; OTTHUMP00000115505 antibody; Phosphoprotein phosphatase 2A BR gamma regulatory chain antibody; PP2A subunit B B gamma isoform antibody; PP2A subunit B B55 gamma isoform antibody; PP2A subunit B isoform B55-gamma antibody; PP2A subunit B isoform gamma antibody; PP2A subunit B isoform PR55-gamma antibody; PP2A subunit B isoform R2-gamma antibody; PP2A subunit B PR55 gamma isoform antibody; PP2A subunit B R2 gamma isoform antibody; PPP2R2C antibody; PPP2R2C protein antibody; PR 52 antibody; PR 55G antibody; PR52 antibody; PR55G antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B gamma isoform antibody; Protein phosphatase 2 regulatory subunit B gamma antibody; Protein phosphatase 2 regulatory subunit B gamma isoform antibody; Protein phosphatase 2A1 B gamma subunit antibody; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform antibody; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform antibody

Raised in

Rabbit

Species Reactivity

Homo sapiens

Immunogen

Recombinant Homo sapiens PPP2R2C protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (12-14 weeks)

Target Background

Function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Gene References into Functions

B55gamma is induced by glucocorticoid receptor in human primary BM-MSCs during differentiation to osteoblast and is required for osteoblast morphogenesis. PMID: 28805158
miR-572 promotes the proliferation and invasion of nasopharyngeal carcinoma by directly down-regulating PPP2R2C PMID: 28525724
miR-1301 promoted prostate cancer proliferation by inhibiting PPP2R2C. PMID: 27261573
These findings provide insights into mechanisms by which prostate cancers resist AR-pathway suppression and support inhibiting PPP2R2C complexes. PMID: 23493267
PPP2R2C is a potential tumor suppressor gene in human brain cancers. PMID: 24126060
evidence suggests that allelic variation in PPP2R2C may be associated with a variety of personality traits and ADHD per se. PMID: 22664926
encoding a subunit of proteinphosphatase 2A with a unique expression pattern in brain and a role in synaptic plasticity PMID: 20601260
specific PP2A complexes involved in human cell transformation PMID: 14998489
novel mechanism of c-SRC regulation whereby in response to stress c-SRC activity is regulated, at least in part, through loss of the interaction with its inhibitor, PR55gamma PMID: 18069897

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Protein Families

Phosphatase 2A regulatory subunit B family

Database Links

HGNC: 9306

OMIM: 605997

KEGG: hsa:5522

STRING: 9606.ENSP00000335083

UniGene: Hs.479069

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PPP2R2C Antibody

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Target Background