PPP2R2C Antibody

Code CSB-PA018566GA01HU
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Product Details

Uniprot No. Q9Y2T4
Target Names PPP2R2C
Alternative Names 2ABG_HUMAN antibody; B55 gamma antibody; Gamma isoform of regulatory subunit B55 protein phosphatase 2 antibody; IMYPNO 1 antibody; IMYPNO antibody; IMYPNO1 antibody; MGC33570 antibody; OTTHUMP00000115505 antibody; Phosphoprotein phosphatase 2A BR gamma regulatory chain antibody; PP2A subunit B B gamma isoform antibody; PP2A subunit B B55 gamma isoform antibody; PP2A subunit B isoform B55-gamma antibody; PP2A subunit B isoform gamma antibody; PP2A subunit B isoform PR55-gamma antibody; PP2A subunit B isoform R2-gamma antibody; PP2A subunit B PR55 gamma isoform antibody; PP2A subunit B R2 gamma isoform antibody; PPP2R2C antibody; PPP2R2C protein antibody; PR 52 antibody; PR 55G antibody; PR52 antibody; PR55G antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B gamma isoform antibody; Protein phosphatase 2 regulatory subunit B gamma antibody; Protein phosphatase 2 regulatory subunit B gamma isoform antibody; Protein phosphatase 2A1 B gamma subunit antibody; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform antibody; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human PPP2R2C
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Gene References into Functions
  1. B55gamma is induced by glucocorticoid receptor in human primary BM-MSCs during differentiation to osteoblast and is required for osteoblast morphogenesis. PMID: 28805158
  2. miR-572 promotes the proliferation and invasion of nasopharyngeal carcinoma by directly down-regulating PPP2R2C PMID: 28525724
  3. miR-1301 promoted prostate cancer proliferation by inhibiting PPP2R2C. PMID: 27261573
  4. These findings provide insights into mechanisms by which prostate cancers resist AR-pathway suppression and support inhibiting PPP2R2C complexes. PMID: 23493267
  5. PPP2R2C is a potential tumor suppressor gene in human brain cancers. PMID: 24126060
  6. evidence suggests that allelic variation in PPP2R2C may be associated with a variety of personality traits and ADHD per se. PMID: 22664926
  7. encoding a subunit of proteinphosphatase 2A with a unique expression pattern in brain and a role in synaptic plasticity PMID: 20601260
  8. specific PP2A complexes involved in human cell transformation PMID: 14998489
  9. novel mechanism of c-SRC regulation whereby in response to stress c-SRC activity is regulated, at least in part, through loss of the interaction with its inhibitor, PR55gamma PMID: 18069897

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Protein Families Phosphatase 2A regulatory subunit B family
Database Links

HGNC: 9306

OMIM: 605997

KEGG: hsa:5522

STRING: 9606.ENSP00000335083

UniGene: Hs.479069

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