TSG101 Antibody

Datasheet
Code CSB-PA860355ZA01HU
Uniprot No. Q99816
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Human Tumor susceptibility gene 101 protein (TSG101), partial (1-145AA)
Raised in Rabbit
Species Reactivity Homo sapiens
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101), TSG101
Immunogen Species Homo sapiens (Human)
Gene Names TSG101
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan
Subcellular Location Cytoplasm, Early endosome membrane, Peripheral membrane protein, Cytoplasmic side, Late endosome membrane, Peripheral membrane protein, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Midbody, Midbody ring, Nucleus
Protein Families Ubiquitin-conjugating enzyme family, UEV subfamily
Tissue Specificity Heart, brain, placenta, lung, liver, skeletal, kidney and pancreas.
Database Links

HGNC: 15971

OMIM: 601387

KEGG: hsa:7251

STRING: 9606.ENSP00000251968

UniGene: Hs.523512

Pathway Endocytosis
Secreted Extracellular Vesicles

Related Products

TSG101 Antibodies

TSG101 Antibodies for Homo sapiens (Human)

TSG101 Proteins

TSG101 Proteins for Homo sapiens (Human)

TSG101 ELISA Kit

TSG101 ELISA Kit for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.