Name: sod1 Antibody
Brand: CUSABIO
SKU: CSB-PA022397ZA01DIL

Product Details

Full Product Name	Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) sod1 Polyclonal antibody
Uniprot No.	O73872
Target Names	sod1
Alternative Names	sod1 antibody; cuzn antibody; Superoxide dismutase [Cu-Zn] antibody; EC 1.15.1.1 antibody
Raised in	Rabbit
Species Reactivity	Danio rerio
Immunogen	Recombinant Danio rerio Superoxide dismutase [Cu-Zn] (sod1) (1-154AA)
Immunogen Species	Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate	Non-conjugated
Clonality	Polyclonal
Isotype	IgG
Purification Method	Protein A/G
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Tested Applications	ELISA, WB (ensure identification of antigen)
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Made-to-order

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Target Data

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Gene References into Functions	fenofibrate almost completely abolished GM-induced reactive oxygen species generation, which seemed to be mediated at least in part by the restoration of the expression of PPARalphadependent antioxidant enzymes, including catalase and superoxide dismutase (SOD)-1. PMID: 28290603 The earliest event in the pathophysiology of amyotrohic lateral sclerosis in the mutant sod1 zebrafish model involves neuronal stress in inhibitory interneurons, resulting from mutant Sod1 expression. PMID: 23281025 A hierarchic gene expression of copper homeostatic genes was demonstrated between atp7a, sp1 and sod1 in zebrafish. PMID: 21167140 depresses cathepsin L activity stimulated by free radicals and prevents otic complications associated with bone erosion PMID: 11771045 This isoform, when expressed in PC-12 cells affects t-butylhydroperoxide-induced apoptosis differentially from its isoenzyme. PMID: 12551919 Copper/zinc superoxide dismutase was cloned from the zebrafish ( Danio rerio). Evidence is presented that SOD protects against paraquat toxicity in fish. PMID: 12876653 Glia maturation factor-null cells ahow a concurrent decrease in CuZnSOD astrocytes. PMID: 15260123 Show More Hide All
Subcellular Location	Cytoplasm, Nucleus
Protein Families	Cu-Zn superoxide dismutase family
Database Links	KEGG: dre:30553 STRING: 7955.ENSDARP00000064375 UniGene: Dr.75822

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Code	CSB-PA022397ZA01DIL
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