Code | CSB-E07419r |
Size | 96T,5×96T,10×96T |
Price | Request a Quote or Start an on-line Chat |
Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now |
The rat MIP-2 ELISA Kit is intended to measure rat MIP-2 in serum, plasma, or tissue homogenates. This assay uses the bi-antibody sandwich technique and enzyme-substrate chromogenic reaction to quantify rat MIP-2 concentration. The intensity of the colored product is directly proportional to the concentration of MIP-2 present in the sample. This rat MIP-2 ELISA kit has high specificity and excellent sensitivity.
MIP-2, also called CXCL2, is a peptide derived from monocytes/ macrophages that attracts and recruits neutrophils to inflamed sites through the p38 MAPK-dependent signaling pathway, by binding to CXCR1 and CXCR2. CXCL2-recruited and activated neutrophils can accelerate liver inflammation by releasing various inflammatory mediators. CXCL2 expression is increased during hepatic I/R injury. Some studies have demonstrated that CXCL2 is overexpressed in breast, colon, prostate, and bladder cancers. While CXCL2 is down-regulated in HCC cell lines, inhibiting hepatocellular carcinoma (HCC) cell proliferation in vitro.
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