CXCL2

CXCL2, also known as C-X-C motif chemokine ligand 2, is commonly referred to as macrophage inflammatory protein-2β (MIP-2β). This protein belongs to the CXC chemokine family and plays a key role in immune response. It functions by binding to CXCR2 receptors, thereby attracting neutrophils to sites of inflammation. This process is involved in the IL-8 signaling pathway, which regulates cell migration and immune cell activation.
Abnormal expression of CXCL2 is associated with various diseases, such as rheumatoid arthritis and certain cancers. In drug development, targeting CXCL2 and its signaling pathway has become a research focus. Some small - molecule inhibitors are under pre - clinical evaluation to explore their potential in treating related diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Human macrophage inflammatory protein 2,MIP-2 ELISA Kit (CSB-E07420h)

Validated Data

Code: CSB-E07420h

Size: 96T,5×96T,10×96T

Sensitivity: 7.81 pg/mL

Detection Range: 3.12 pg/mL-200 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following CXCL2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CXCL2 Antibodies

CXCL2 Proteins

CXCL2 ELISA Kits

CXCL2 Antibodies

CXCL2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA08989A0Rb	CXCL2 Antibody	Human	ELISA
CSB-PA08989B0Rb	CXCL2 Antibody, HRP conjugated	Human	ELISA
CSB-PA08989C0Rb	CXCL2 Antibody, FITC conjugated	Human
CSB-PA08989D0Rb	CXCL2 Antibody, Biotin conjugated	Human	ELISA

CXCL2 Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA092274ZA01MO	Cxcl2 Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

CXCL2 Proteins

CXCL2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP006248MO CSB-EP006248MO CSB-BP006248MO CSB-MP006248MO CSB-EP006248MO-B	Recombinant Mouse C-X-C motif chemokine 2 (Cxcl2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001071MO	Recombinant Mouse C-X-C motif chemokine 2 protein (Cxcl2) (Active)	E.coli
CSB-RP092274m	Recombinant Mouse C-X-C motif chemokine 2 protein (Cxcl2)	E.coli

CXCL2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP006248HU CSB-BP006248HU CSB-MP006248HU CSB-EP006248HU-B	Recombinant Human C-X-C motif chemokine 2 (CXCL2)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP000641HU	Recombinant Human C-X-C motif chemokine 2 protein (CXCL2)	E.Coli
CSB-AP003541HU	Recombinant Human C-X-C motif chemokine 2 (CXCL2), partial (Active)	E.coli
CSB-EP006248HU	Recombinant Human C-X-C motif chemokine 2 (CXCL2)	E.coli

CXCL2 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP006248RA CSB-EP006248RA CSB-BP006248RA CSB-MP006248RA CSB-EP006248RA-B	Recombinant Rat C-X-C motif chemokine 2 (Cxcl2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001401RA	Recombinant Rat C-X-C motif chemokine 2 protein (Cxcl2), partial (Active)	E.coli