Recombinant Human Tumor necrosis factor receptor superfamily member 4(TNFRSF4),partial (Active)

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Code CSB-AP005241HU
Product Type Immune Checkpoint
Size $124Purchase it in Cusabio online store
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Uniprot No. P43489
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4
Alias Tumor necrosis factor receptor superfamily member 4;TNFRSF4;OX40;CD134;Txgp1
Species Homo sapiens (Human)
Biological_Activity The ED50 as determined by its ability to bind Human TNFSF4 in functional ELISA is less than 25 ug/ml.
Purity Greater than 95% as determined by SDS-PAGE.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence LHCVGDTYPSNDRCCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQPQETQGPPARPITVQPTEAWPRTSQGPSTRPVEVPGGRAVA
Research Area Cancer
Source Mammalian cell
Gene Names TNFRSF4
Expression Region 29-216aa
Tag Info C-terminal 6xHis-tagged
Mol. Weight 21 kDa
Protein Description Partial
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Function Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.
Involvement in disease Immunodeficiency 16 (IMD16)
Subcellular Location Membrane, Single-pass type I membrane protein
Database Links

HGNC: 11918

OMIM: 600315

KEGG: hsa:7293

STRING: 9606.ENSP00000368538

UniGene: Hs.129780

Pathway Target Therapy

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