TNFRSF4, usually called CD134 and OX40 receptor, is a member of the TNFR-superfamily of receptors for TNFSF4/OX40L/GP34 and is a costimulatory molecule implicated in long-term T-cell immunity. Unlike CD28, this receptor is not constitutively expressed on resting naïve T cells. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels.

TNFRSF4 Antibodies

TNFRSF4 Antibodies for Homo sapiens (Human)

TNFRSF4 Antibodies for Mus musculus (Mouse)

TNFRSF4 Proteins

TNFRSF4 Proteins for Mus musculus (Mouse)

TNFRSF4 Proteins for Homo sapiens (Human)

TNFRSF4 Proteins for Rattus norvegicus (Rat)


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