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The CDH1 monoclonal antibody is a highly specific and sensitive tool for detecting human CDH1 expression in biological samples. Its synthesis is based on the hybridoma technology. The recombinant human CDH1 protein (155-707aa) is used to immunize the mouse to isolate the mouse spleen cells, which are fused with myeloma cells to create hybridomas. CDH1 antibody-producing hybridomas are selected to culture and harvest the desired antibodies. After protein G purification, this CDH1 monoclonal antibody exceeds 95% in purity. Four applications ELISA, WB, IF, and FC have been done to verify the specificity of this CDH1 antibody.
CDH1 plays a critical role in cell adhesion and tissue architecture in epithelial tissues. CDH1 protein regulates various cellular processes such as cell differentiation, proliferation, and apoptosis. It also has a crucial role in maintaining the polarity and integrity of epithelial tissues.
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