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The generation of the recombinant monoclonal antibody specific to CDH1 involves the initial step of inserting CDH1 antibody genes into plasmid vectors. These recombinant plasmid vectors are then introduced into appropriate host cells for expression using exogenous protein expression technology. Following this, the CDH1 recombinant monoclonal antibody is subject to purification using affinity chromatography. It has been meticulously validated for multiple applications, including ELISA, WB, and IHC. Notably, this antibody exhibits reactivity with both human and mouse CDH1 proteins.
CDH1 (E-cadherin) is a fundamental protein that governs calcium-dependent cell-cell adhesion in epithelial tissues. Its primary function is to promote tissue integrity, control cell behavior, and participate in developmental processes. Dysfunction or loss of CDH1 function can have significant implications for tissue stability and is associated with various diseases, including cancer.
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