ABAT Antibody

Datasheet
Code CSB-PA001032ESR1HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P80404
Image
  • Western blot
    All lanes: 4-aminobutyrate aminotransferase, mitochondrial antibody at 10μg/ml
    Lane 1: Rat liver tissue
    Lane 2: Mouse pancreatic tissue
    Lane 3: Mouse kidney tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 56 kDa
    Observed band size: 56 kDa

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001032ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA001032ESR1HU at dilution of 1:100

Immunogen Recombinant Human 4-aminobutyrate aminotransferase, mitochondrial protein (29-300AA)
Raised in Rabbit
Species Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200
Relevance Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
Form Liquid
Conjugate Non-conjugated
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method Antigen Affinity purified
Isotype IgG
Clonality Polyclonal
Alias 4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT), ABAT, GABAT
Immunogen Species Human
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Research Area Neuroscience
Target Names ABAT
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
Involvement in disease GABA transaminase deficiency (GABATD)
Subcellular Location Mitochondrion matrix
Protein Families Class-III pyridoxal-phosphate-dependent aminotransferase family
Tissue Specificity Liver > pancreas > brain > kidney > heart > placenta.
Database Links

HGNC: 23

OMIM: 137150

KEGG: hsa:18

STRING: 9606.ENSP00000268251

UniGene: Hs.336768

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