AR Antibody

Datasheet
Code CSB-PA006094
Size US$167
Uniprot No. P10275
Image
  • Western Blot analysis of Hela cells using AR Polyclonal Antibody.
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from the Internal region of Human AR.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications WB,ELISA;WB:1/500-1/2000.ELISA:1/10000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias AR; DHTR; NR3C4; Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4
Immunogen Species Homo sapiens (Human)
Target Names AR
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
Involvement in disease Androgen insensitivity syndrome (AIS); Spinal and bulbar muscular atrophy X-linked 1 (SMAX1); Androgen insensitivity, partial (PAIS)
Subcellular Location Nucleus, Cytoplasm
Protein Families Nuclear hormone receptor family, NR3 subfamily
Tissue Specificity Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107).
Database Links

HGNC: 644

OMIM: 300068

KEGG: hsa:367

STRING: 9606.ENSP00000363822

UniGene: Hs.76704

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