ARL2BP Antibody

Datasheet
Code CSB-PA897097HA01HU
See More Details Free Antibody trial simple
Size US$299
Uniprot No. Q9Y2Y0
Image
  • Western Blot
    Positive WB detected in: HepG2 whole cell lysate, U251 whole cell lysate, U87 whole cell lysate
    All lanes: ARL2BP antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 19, 18 kDa
    Observed band size: 19 kDa

  • IHC image of CSB-PA897097HA01HU diluted at 1:100 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human ADP-ribosylation factor-like protein 2-binding protein (1-163AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200
Relevance Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) (ARL2-binding protein) (Binder of ARF2 protein 1), ARL2BP, BART BART1
Immunogen Species Homo sapiens (Human)
Research Area Signal Transduction
Target Names ARL2BP
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
Involvement in disease Retinitis pigmentosa with or without situs inversus (RPSI)
Subcellular Location Cytoplasm, Mitochondrion intermembrane space, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Nucleus, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, cilium basal body
Protein Families ARL2BP family
Tissue Specificity Expressed in retina pigment epithelial cells (at protein level). Widely expressed.
Database Links

HGNC: 17146

OMIM: 615407

KEGG: hsa:23568

STRING: 9606.ENSP00000219204

UniGene: Hs.632873

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