Acetyl-CREBBP (K1535) Antibody

Datasheet
Code CSB-PA000107
Size US$167
Uniprot No. Q92793
Image
  • Western Blot analysis of various cells using Acetyl-CBP (K1535) Polyclonal Antibody
Immunogen Synthesized peptide derived from Human CBP around the acetylation site of K1535.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications WB,IHC,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias CREBBP; CBP; CREB-binding protein
Immunogen Species Homo sapiens (Human)
Protocols Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
Target Names CREBBP
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators
Involvement in disease Rubinstein-Taybi syndrome 1 (RSTS1)
Subcellular Location Cytoplasm, Nucleus
Database Links

HGNC: 2348

OMIM: 180849

KEGG: hsa:1387

STRING: 9606.ENSP00000262367

UniGene: Hs.459759

Pathway cAMP signaling pathway
HIF-1 signaling pathway
Jak-STAT signaling pathway
Melanogenesis
Notch signaling pathway
TGF-beta signaling pathway
Wnt signaling pathway
Adherens junction
Cell cycle
FoxO signaling pathway
Glucagon signaling pathway

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