CCT2 Antibody

Code CSB-PA004856ESR1HU
Size US$166
Order now
Image
  • Western blot
    All lanes: CCT2 antibody at 5.63μg/ml
    Lane 1: Jurkat whole cell lysate
    Lane 2: NIH/3T3 whole cell lysate
    Lane 3: MCF-7 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 58, 53 kDa
    Observed band size: 58 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA004856ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA004856ESR1HU at dilution of 1:100

  • Immunoprecipitating CCT2 in Jurkat whole cell lysate
    Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA004856ESR1HU in Jurkat whole cell lysate. For western blotting, a HRP-conjugated light chain specific antibody was used as the Secondary antibody (1/50000)
    Lane 2: CSB-PA004856ESR1HU (4μg) + Jurkat whole cell lysate (500μg)
    Lane 3: Jurkat whole cell lysate (20μg)

Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CCT2 Polyclonal antibody
Uniprot No.
Target Names
CCT2
Alternative Names
99D8.1 antibody; CCT 2 antibody; CCT beta antibody; CCT-beta antibody; CCT2 antibody; CCTB antibody; Chaperonin containing t complex polypeptide 1 beta subunit antibody; Chaperonin containing t complex polypeptide 1 subunit 2 antibody; Chaperonin containing TCP1 subunit 2 antibody; Chaperonin containing TCP1 subunit 2 (beta) antibody; CTP:phosphocholine cytidylyltransferase 2 antibody; Epididymis secretory sperm binding protein Li 100n antibody; HEL S 100n antibody; MGC142074 antibody; MGC142076 antibody; MGC94480 antibody; PRO1633 antibody; T complex protein 1 beta subunit antibody; T complex protein 1 subunit beta antibody; T-complex protein 1 subunit beta antibody; TCP 1 beta antibody; TCP-1-beta antibody; TCPB_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human T-complex protein 1 subunit beta protein (206-535AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC, IP
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IP 1:200-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
Gene References into Functions
  1. the novel LCA mutations in CCTbeta and the impact of chaperon disability by these mutations in cellular biology. PMID: 27645772
  2. A role for the TRiC subunits TCP1 and CCT2, and potentially the entire TRiC complex, in breast cancer. PMID: 25704758
  3. Increased expression of CCT2 is associated with tumor progression and the clinical behavior of gallbladder carcinoma. PMID: 23782473
  4. PDCD5 bound the apical domain of the CCTbeta subunit, projecting above the folding cavity without entering it. Like PDCD5, beta-tubulin also interacts with the CCTbeta apical domain, but a second site is found at the sensor loop deep within the folding cavity. PMID: 24375412
  5. PB2 associates with CCT2 as a monomer and the CCT binding site is located in a central region of the PB2 protein. PMID: 20573828
  6. The chaperonin CCT is identified as a novel physiological substrate for p90 ribosomal S6 kinase (RSK) and p70 ribosomal S6 kinase (S6K). PMID: 19332537

Show More

Hide All

Subcellular Location
Cytoplasm.
Protein Families
TCP-1 chaperonin family
Database Links

HGNC: 1615

OMIM: 605139

KEGG: hsa:10576

STRING: 9606.ENSP00000299300

UniGene: Hs.189772

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*