CHRM5 Antibody

Datasheet

Code	CSB-PA005385LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Mouse liver tissue, Mouse kidney tissue, Mouse brain tissue All lanes: CHRM5 antibody at 3.5μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 61 kDa Observed band size: 61 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA005385LA01HU at dilution of 1:100 Immunofluorescent analysis of A549 cells using CSB-PA005385LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CHRM5 Polyclonal antibody

Uniprot No.

P08912

Target Names

CHRM5

Alternative Names

CHRM5; Muscarinic acetylcholine receptor M5

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Muscarinic acetylcholine receptor M5 protein (220-427AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CHRM5 Antibody (Product code: CSB-PA005385LA01HU) is Non-conjugated. For CHRM5 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA005385LB01HU	CHRM5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA005385LC01HU	CHRM5 Antibody, FITC conjugated
Biotin	CSB-PA005385LD01HU	CHRM5 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

Gene References into Functions

Immunological stimulation leads to M5 mAChR gene expression in lymphocytes. PMID: 12675126
direct evidence suggesting that the M5 muscarinic receptor gene combined with the alpha7-nicotinic receptor gene may be linked to schizophrenia PMID: 15292665
mAChR subtypes (m1 to m5)presents in human scleral fibroblasts at both mRNA and protein levels. PMID: 16877267
the first study to show an association between CHRM5 and substance use in humans PMID: 17608938

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM5 sub-subfamily

Database Links

HGNC: 1954

OMIM: 118496

KEGG: hsa:1133

STRING: 9606.ENSP00000372750

UniGene: Hs.584747

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Service

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Antibody Service

Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Calcium signaling pathway Regulation of actin cytoskeleton G protein coupled receptor signaling pathway

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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